Protein: Q53FC7
Heat shock 70 kDa protein 6

Gene: Q53FC7
Organism: Homo sapiens
Interactions: 57
UniProt ID: Q53FC7

Gene Ontology (top 5):
GO:0005524 - ATP binding
GO:0140662 - ATP-dependent protein folding chaperone

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

930913

HSP72
Heat shock-related 70 kDa protein 2

1

13

High-throughput

0.618

High

336682

BAG4
BAG family molecular chaperone regulator 4

1

20

High-throughput

0.553

High

347739

BAG3
BAG family molecular chaperone regulator 3

1

20

High-throughput

0.553

High

679346

DNJB2
DnaJ homolog subfamily B member 2

1

20

High-throughput

0.553

High

1198795

BAG1
BAG family molecular chaperone regulator 1

1

6

High-throughput

0.553

High

1198803

BAG5
BAG family molecular chaperone regulator 5

1

20

High-throughput

0.553

High

69438

A8K2M0
26S proteasome regulatory subunit 6B

1

4

High-throughput

0.479

High

363375

EGFR
Epidermal growth factor receptor

1

16

High-throughput

0.479

High

364142

MOS
Proto-oncogene serine/threonine-protein kinase mos

1

2

High-throughput

0.479

High

400933

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

11

High-throughput

0.479

High

410884

ERBB2
Receptor tyrosine-protein kinase erbB-2

1

12

High-throughput

0.479

High

756228

MCM7
DNA replication licensing factor MCM7

1

10

High-throughput

0.479

High

947354

NAL12
NACHT, LRR and PYD domains-containing protein 12

1

10

High-throughput

0.479

High

1122502

IKKE
Inhibitor of nuclear factor kappa-B kinase subunit epsilon

1

14

High-throughput

0.479

High

1198783

Q5T853
Mitogen-activated protein kinase kinase kinase 8

1

2

High-throughput

0.479

High

1198793

PSKH2
Serine/threonine-protein kinase H2

1

4

High-throughput

0.479

High

1198796

AASD1
Alanyl-tRNA editing protein Aarsd1

1

2

High-throughput

0.479

High

1198799

E2AK4
eIF-2-alpha kinase GCN2

1

8

High-throughput

0.479

High

1198805

Q9UMP2
DNA mismatch repair protein

1

3

High-throughput

0.479

High

1198806

NOD1
Nucleotide-binding oligomerization domain-containing protein 1

1

10

High-throughput

0.479

High

1180056

Q2TAK1
F-box DNA helicase 1

1

0

High-throughput

0.458

High

1198791

Q93000
CHL1 protein

1

0

High-throughput

0.458

High

193024

CFLAR
CASP8 and FADD-like apoptosis regulator

1

3

High-throughput

0.437

High

347076

BAG2
BAG family molecular chaperone regulator 2

1

7

High-throughput

0.437

High

983503

GBB1
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1

1

13

High-throughput

0.437

High

1083496

TEF
Thyrotroph embryonic factor

1

8

High-throughput

0.437

High

1098010

PSMD2
26S proteasome non-ATPase regulatory subunit 2

1

3

High-throughput

0.437

High

1101831

SKP2
S-phase kinase-associated protein 2

1

10

High-throughput

0.437

High

1153041

TAB1
TGF-beta-activated kinase 1 and MAP3K7-binding protein 1

1

4

High-throughput

0.437

High

1169053

Q1MSW8
Cellular tumor antigen p53

1

6

High-throughput

0.437

High

1187295

Q3MSN4
Nuclear receptor subfamily 3 group C member 1

1

1

High-throughput

0.437

High

1196055

Q4TT70
Regulator of G-protein signaling 11

1

1

High-throughput

0.437

High

1198778

Q53XS2
Ectodermal-neural cortex

1

5

High-throughput

0.437

High

1198779

Q59FP4
Integrin-linked kinase variant

1

5

High-throughput

0.437

High

1198780

Q5C8S5
Estrogen receptor alpha mamillary body 1 isoform

1

4

High-throughput

0.437

High

1198784

DET1
DET1 homolog

1

1

High-throughput

0.437

High

1198786

DAA11
Dynein axonemal assembly factor 11

1

9

High-throughput

0.437

High

1198787

CC117
Coiled-coil domain-containing protein 117

1

6

High-throughput

0.437

High

1198788

CTCFL
Transcriptional repressor CTCFL

1

4

High-throughput

0.437

High

1198789

Q8TA90
Elongation factor 2

1

4

High-throughput

0.437

High

1198790

Q8WYX9
Uncharacterized protein pp10122

1

1

High-throughput

0.437

High

1198792

ARMC5
Armadillo repeat-containing protein 5

1

6

High-throughput

0.437

High

1198794

PFD5
Prefoldin subunit 5

1

1

High-throughput

0.437

High

1198797

Q9BZG7
Androgen receptor

1

1

High-throughput

0.437

High

1198798

Q9HAV2
Heat shock transcription factor 1

1

8

High-throughput

0.437

High

1198800

HDAC6
Protein deacetylase HDAC6

1

12

High-throughput

0.437

High

1198801

HSPB8
Heat shock protein beta-8

1

5

High-throughput

0.437

High

1198802

FBXW2
F-box/WD repeat-containing protein 2

1

10

High-throughput

0.437

High

1198804

ZN215
Zinc finger protein 215

1

6

High-throughput

0.437

High

1198807

TRI17
E3 ubiquitin-protein ligase TRIM17

1

7

High-throughput

0.437

High

281498

FBX24
F-box only protein 24

1

0

High-throughput

0.249

Low

907674

CLCN2
Chloride channel protein 2

1

0

High-throughput

0.249

Low

1129144

IRF3
Interferon regulatory factor 3

1

0

High-throughput

0.249

Low

1142240

CD5R1
Cyclin-dependent kinase 5 activator 1

1

0

High-throughput

0.249

Low

1198781

Q5T6U8
High mobility group protein HMG-I/HMG-Y

1

0

High-throughput

0.249

Low

1198782

Q5T7U4
General transcription factor IIIC subunit 5

1

0

High-throughput

0.249

Low

1198785

GTD2A
General transcription factor II-I repeat domain-containing protein 2A

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025