Interactor 1: NR2C1 (P13056)
Nuclear receptor subfamily 2 group C member 1 (Orphan nuclear receptor TR2) (Testicular receptor 2)
Gene: NR2C1

Interactor 2: NR2C2 (P49116)
Nuclear receptor subfamily 2 group C member 2 (Orphan nuclear receptor TAK1) (Orphan nuclear receptor TR4) (Testicular receptor 4)
Gene: NR2C2

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.62 1.00 0.789

The method score is based on:

Property Details
Experiments 30463901, 21670149
Identification Methods affinity chromatography technology, biochemical
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains Hormone_recep~Hormone_recep, Hormone_recep~zf-C4, zf-C4~zf-C4
Common GO terms GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000785 - chromatin
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0004879 - nuclear receptor activity
and 4 others

more...

Homologous interactions 16

Homologous interactions

Color coding for hit scores

1 603
Hs

1 596
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024