HitPredict

Interactor 1: NR2C1 (P13056)
Nuclear receptor subfamily 2 group C member 1 (Orphan nuclear receptor TR2) (Testicular receptor 2)
Gene: NR2C1

Interactor 2: ELF2 (Q15723)
ETS-related transcription factor Elf-2 (E74-like factor 2) (New ETS-related factor)
Gene: ELF2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	35140242
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000785 - chromatin GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific GO:0005654 - nucleoplasm GO:0030154 - cell differentiation GO:1990837 - sequence-specific double-stranded DNA binding
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 603 Hs			1 593
+	Hs
		824051 NR2C2_HUMAN (11-603): 4.85e-143: 429: 59.80		ELF2_HUMAN (1-593): 1.28e-108: 339: 100.00
+	Hs
		525286 NR2C1_HUMAN (1-603): 1.16e-165: 487: 100.00		ELF1_HUMAN (3-589): 1.89e-55: 199: 33.17
+	Hs
		823921 NR2C2_HUMAN (11-603): 4.85e-143: 429: 59.80		GABPA_HUMAN (33-343): 2.16e-75: 249: 20.99
+	Hs
		525338 NR2C1_HUMAN (1-603): 1.16e-165: 487: 100.00		ETV7_HUMAN (30-325): 1.2e-45: 166: 16.95
+	Hs
		525331 NR2C1_HUMAN (1-603): 1.16e-165: 487: 100.00		FEV_HUMAN (162-404): 5.27e-45: 161: 20.17
+	Hs
		525289 NR2C1_HUMAN (1-603): 1.16e-165: 487: 100.00		ETV3_HUMAN (181-592): 7.1e-37: 145: 20.35
+	Hs
		824305 NR2C2_HUMAN (11-603): 4.85e-143: 429: 59.80		FEV_HUMAN (162-404): 5.27e-45: 161: 20.17
+	Hs
		781160 NR2C2_HUMAN (11-603): 4.85e-143: 429: 59.80		ETV3_HUMAN (181-592): 7.1e-37: 145: 20.35
+	Hs
		782554 HNF4A_HUMAN (59-228): 7.55e-43: 162: 33.53		ELF2_HUMAN (1-593): 1.28e-108: 339: 100.00
+	Dm
		1096236 HR78_DROME (85-595): 4.34e-78: 260: 26.29		ET96B_DROME (94-340): 7.9e-43: 164: 20.40
+	Dm
		558424 7UP1_DROME (54-189): 8.06e-40: 154: 44.85		ETS6_DROME (39-291): 1.73e-34: 138: 20.16