Protein: HBT1
Protein HBT1 (HUB1 target protein 1)

Gene: HBT1
Organism: Saccharomyces cerevisiae S288C
Interactions: 91
UniProt ID: Q07653

Gene Ontology (top 5):
GO:0000753 - cell morphogenesis involved in conjugation with cellular fusion
GO:0005737 - cytoplasm
GO:0005886 - plasma membrane
GO:0005937 - mating projection
GO:0008360 - regulation of cell shape

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

393418

HSP82
ATP-dependent molecular chaperone HSP82

3

1

High-throughput

0.640

High

525319

HSP71
Heat shock protein SSA1

3

1

High-throughput

0.640

High

580157

HSC82
ATP-dependent molecular chaperone HSC82

2

1

Small-scale

0.584

High

527820

HSP72
Heat shock protein SSA2

2

1

High-throughput

0.571

High

748074

SMY2
Protein SMY2

2

0

High-throughput

0.559

High

740019

CDC5
Cell cycle serine/threonine-protein kinase CDC5/MSD2

1

0

Small-scale

0.513

High

656645

KC11
Casein kinase I homolog 1

1

1

High-throughput

0.501

High

656895

KC12
Casein kinase I homolog 2

1

1

High-throughput

0.501

High

441272

KAPA
cAMP-dependent protein kinase type 1

1

0

High-throughput

0.480

High

758338

HSL1
Probable serine/threonine-protein kinase HSL1

1

0

High-throughput

0.480

High

825434

PRK1
Actin-regulating kinase PRK1

1

0

High-throughput

0.480

High

865554

PTK2
Serine/threonine-protein kinase PTK2/STK2

1

0

High-throughput

0.480

High

1030260

BCK1
Serine/threonine-protein kinase BCK1/SLK1/SSP31

1

0

High-throughput

0.480

High

1040427

FRK1
Fatty acyl-CoA synthetase and RNA processing-associated kinase 1

1

0

High-throughput

0.480

High

742519

HSP7F
Heat shock protein homolog SSE1

1

2

High-throughput

0.479

High

94588

STE2
Pheromone alpha factor receptor

1

0

High-throughput

0.458

High

510860

HSP77
Import motor subunit, mitochondrial

1

0

High-throughput

0.458

High

556582

STE6
Alpha-factor-transporting ATPase

1

0

High-throughput

0.458

High

584394

GCN2
eIF-2-alpha kinase GCN2

1

0

High-throughput

0.458

High

590735

HSP26
Heat shock protein 26

1

0

High-throughput

0.458

High

624814

PMA2
Plasma membrane ATPase 2

1

0

High-throughput

0.458

High

632399

CG11
G1/S-specific cyclin CLN1

1

0

High-throughput

0.458

High

667065

CG21
G2/mitotic-specific cyclin-1

1

0

High-throughput

0.458

High

672961

RRP43
Exosome complex component RRP43

1

0

High-throughput

0.458

High

678847

AHC2
ADA histone acetyltransferase complex component 2

1

0

High-throughput

0.458

High

711532

BEM1
Bud emergence protein 1

1

0

High-throughput

0.458

High

751883

SLA2
Protein SLA2

1

0

High-throughput

0.458

High

752800

HSP78
Heat shock protein 78, mitochondrial

1

0

High-throughput

0.458

High

761140

NOT4
General negative regulator of transcription subunit 4

1

0

High-throughput

0.458

High

802051

HXT5
Probable glucose transporter HXT5

1

0

High-throughput

0.458

High

817251

EDC2
Enhancer of mRNA-decapping protein 2

1

0

High-throughput

0.458

High

850024

LOC1
60S ribosomal subunit assembly/export protein LOC1

1

0

High-throughput

0.458

High

863404

RSF2
Respiration factor 2

1

0

High-throughput

0.458

High

864276

ALY2
Arrestin-related trafficking adapter 3

1

0

High-throughput

0.458

High

864841

MPS3
Spindle pole body assembly component MPS3

1

0

High-throughput

0.458

High

918596

TWF1
Twinfilin-1

1

0

High-throughput

0.458

High

919140

VSB1
Vacuolar basic amino acid transporter VSB1

1

0

High-throughput

0.458

High

919270

YG3A
Uncharacterized protein YGR130C

1

0

High-throughput

0.458

High

1042559

VPS60
Vacuolar protein-sorting-associated protein 60

1

0

Small-scale

0.458

High

1044126

MSS11
Transcription activator MSS11

1

0

High-throughput

0.458

High

1049964

YDR22
SVF1-like protein YDR222W

1

0

High-throughput

0.458

High

1050319

EIS1
Eisosome protein 1

1

0

High-throughput

0.458

High

1059772

FMP45
SUR7 family protein FMP45

1

0

High-throughput

0.458

High

1059789

ARP8
Actin-like protein ARP8

1

0

High-throughput

0.458

High

1059790

RTN2
Reticulon-like protein 2

1

0

High-throughput

0.458

High

1059792

HUB1
Ubiquitin-like modifier HUB1

1

0

Small-scale

0.458

High

925093

APJ1
J domain-containing protein APJ1

1

0

High-throughput

0.426

High

917946

PDK2
[Pyruvate dehydrogenase

1

0

High-throughput

0.261

Low

480002

PRTB
Cerevisin

1

0

High-throughput

0.249

Low

577581

CYC8
General transcriptional corepressor CYC8

1

0

High-throughput

0.249

Low

583166

CUP2
Transcriptional activator protein CUP2

1

0

High-throughput

0.249

Low

598446

TUP1
General transcriptional corepressor TUP1

1

0

High-throughput

0.249

Low

633197

MAK11
Protein MAK11

1

0

High-throughput

0.249

Low

670208

MRM1
rRNA methyltransferase 1, mitochondrial

1

0

High-throughput

0.249

Low

680108

CDC48
Cell division control protein 48

1

0

High-throughput

0.249

Low

693503

CBPS
Carboxypeptidase S

1

0

High-throughput

0.249

Low

698125

PEP3
Vacuolar membrane protein PEP3

1

0

High-throughput

0.249

Low

726120

PMT2
Dolichyl-phosphate-mannose--protein mannosyltransferase 2

1

0

High-throughput

0.249

Low

776434

YKG3
Uncharacterized protein YKL063C

1

0

High-throughput

0.249

Low

781537

VPS51
Vacuolar protein sorting-associated protein 51

1

0

High-throughput

0.249

Low

782114

RL1D1
Ribosome biogenesis protein UTP30

1

0

High-throughput

0.249

Low

792975

ANM1
Protein arginine N-methyltransferase 1

1

0

High-throughput

0.249

Low

795969

RRN10
RNA polymerase I-specific transcription initiation factor RRN10

1

0

High-throughput

0.249

Low

797364

ICS2
Increased copper sensitivity protein 2

1

0

High-throughput

0.249

Low

797590

FZO1
Mitofusin FZO1

1

0

High-throughput

0.249

Low

802499

LAG1
Ceramide synthase LAG1

1

0

High-throughput

0.249

Low

804832

PP2C7
Protein phosphatase 2C homolog 7, mitochondrial

1

0

High-throughput

0.249

Low

808923

UME6
Transcriptional regulatory protein UME6

1

0

High-throughput

0.249

Low

812706

LAA1
AP-1 accessory protein LAA1

1

0

High-throughput

0.249

Low

816952

PPOX
Protoporphyrinogen oxidase

1

0

High-throughput

0.249

Low

818534

SPI1
Uncharacterized cell wall protein SPI1

1

0

High-throughput

0.249

Low

824878

NDC80
Kinetochore protein NDC80

1

0

High-throughput

0.249

Low

826881

DSN1
Kinetochore-associated protein DSN1

1

0

High-throughput

0.249

Low

850225

RPN11
Ubiquitin carboxyl-terminal hydrolase RPN11

1

0

High-throughput

0.249

Low

850589

RSC8
Chromatin structure-remodeling complex protein RSC8

1

0

High-throughput

0.249

Low

867864

SSN8
RNA polymerase II holoenzyme cyclin-like subunit

1

0

High-throughput

0.249

Low

881457

TOM22
Mitochondrial import receptor subunit TOM22

1

0

High-throughput

0.249

Low

916973

COG1
Conserved oligomeric Golgi complex subunit 1

1

0

High-throughput

0.249

Low

917719

USE1
Protein transport protein USE1

1

0

High-throughput

0.249

Low

923282

BIO5
7-keto 8-aminopelargonic acid transporter

1

0

High-throughput

0.249

Low

925391

SAM50
Sorting assembly machinery 50 kDa subunit

1

0

High-throughput

0.249

Low

1040260

YP109
ABC1 family protein YPL109C, mitochondrial

1

0

High-throughput

0.249

Low

1044156

GIS1
Transcriptional activator/repressor GIS1

1

0

High-throughput

0.249

Low

1059785

HRD1
ERAD-associated E3 ubiquitin-protein ligase HRD1

1

0

High-throughput

0.249

Low

1059786

CFT2
Cleavage factor two protein 2

1

0

High-throughput

0.249

Low

1059787

ATG9
Autophagy-related protein 9

1

0

High-throughput

0.249

Low

1059788

EMA19
Efficient mitochondria targeting-associated protein 19

1

0

High-throughput

0.249

Low

1059791

CENPI
Inner kinetochore subunit CTF3

1

0

High-throughput

0.249

Low

1059793

BRR1
Pre-mRNA-splicing factor BRR1

1

0

High-throughput

0.249

Low

574934

SAM35
Sorting assembly machinery 35 kDa subunit

1

0

High-throughput

0.238

Low

1035138

UBC7
Ubiquitin-conjugating enzyme E2 7

1

0

High-throughput

0.238

Low


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Last updated: 11Aug2025