HitPredict

Interactor 1: ESM5 (P13096)
Enhancer of split m5 protein (E(spl)m5)
Gene: E(spl)m5-HLH

Interactor 2: EGON (P15370)
Protein embryonic gonad (Nuclear receptor subfamily 0 group A member 3) (Protein eagle) (Protein spready)
Gene: eg

Species: Drosophila melanogaster

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.43	0.60	0.508

Property	Details
Experiments	14605208
Identification Methods	two hybrid
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0006357 - regulation of transcription by RNA polymerase II GO:0030154 - cell differentiation
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 178 Dm			1 373
+	Dm
		548013 ESMB_DROME (9-178): 3.08e-51: 164: 32.49		EGON_DROME (1-373): 0: 528: 100.00
+	Mm
		659672 HES1_MOUSE (2-138): 3.08e-52: 169: 23.78		RXRA_MOUSE (3-84): 1.95e-44: 161: 37.81
+	Hs
		146498 BHE40_HUMAN (4-175): 9.06e-39: 138: 15.71		NR1D2_HUMAN (1-161): 2.9e-49: 176: 31.06
+	Hs
		146455 BHE40_HUMAN (4-175): 9.06e-39: 138: 15.71		RXRA_HUMAN (3-84): 2.14e-44: 161: 37.81
+	Hs
		146528 BHE40_HUMAN (4-175): 9.06e-39: 138: 15.71		RORB_HUMAN (4-95): 2.11e-43: 158: 40.22
+	Hs
		587197 BHE41_HUMAN (6-174): 1.3e-36: 133: 16.04		RXRA_HUMAN (3-84): 2.14e-44: 161: 37.81
+	Hs
		369025 ARNT_HUMAN (4-89): 1.78e-21: 92.6: 16.28		ESR1_HUMAN (3-161): 7.73e-56: 194: 32.35
+	Hs
		649141 ARNT_HUMAN (4-89): 1.78e-21: 92.6: 16.28		ESR2_HUMAN (3-160): 5.4e-46: 166: 29.11
+	Hs
		649056 ARNT_HUMAN (4-89): 1.78e-21: 92.6: 16.28		HNF4A_HUMAN (1-138): 5.23e-45: 163: 25.34
+	Hs
		126095 BMAL1_HUMAN (20-93): 1.65e-12: 66.3: 21.62		GCR_HUMAN (2-191): 1.11e-49: 180: 26.43
+	Dm
		799530 HEY_DROME (1-175): 9.04e-44: 151: 21.43		E78C_DROME (5-80): 2.64e-16: 82.4: 46.05
+	Hs
		126108 BMAL1_HUMAN (20-93): 1.65e-12: 66.3: 21.62		HNF4A_HUMAN (1-138): 5.23e-45: 163: 25.34
+	Hs
		126103 BMAL1_HUMAN (20-93): 1.65e-12: 66.3: 21.62		RXRA_HUMAN (3-84): 2.14e-44: 161: 37.81
+	Dm
		534342 HAIR_DROME (1-166): 1.22e-39: 139: 23.98		E78C_DROME (5-80): 2.64e-16: 82.4: 46.05
+	Hs
		146467 BHE40_HUMAN (4-175): 9.06e-39: 138: 15.71		RORG_HUMAN (5-82): 7.52e-16: 80.9: 44.87
+	Hs
		723195 BHE41_HUMAN (6-174): 1.3e-36: 133: 16.04		RORA_HUMAN (5-82): 2.33e-17: 85.1: 44.87
+	Hs
		846426 BHE41_HUMAN (6-174): 1.3e-36: 133: 16.04		RORG_HUMAN (5-82): 7.52e-16: 80.9: 44.87
+	Dm
		247694 CYCL_DROME (15-95): 5.86e-24: 98.7: 16.05		E78C_DROME (5-80): 2.64e-16: 82.4: 46.05
+	Hs
		846420 BMAL2_HUMAN (5-95): 2.73e-21: 91.8: 17.71		RORG_HUMAN (5-82): 7.52e-16: 80.9: 44.87
+	Hs
		126112 BMAL1_HUMAN (20-93): 1.65e-12: 66.3: 21.62		RORG_HUMAN (5-82): 7.52e-16: 80.9: 44.87