Protein: DPH3
Diphthamide biosynthesis protein 3 (Kluyveromyces lactis toxin-insensitive protein 11)

Gene: DPH3, KTI11
Organism: Saccharomyces cerevisiae S288C
Interactions: 37
UniProt ID: Q3E840

Gene Ontology (top 5):
GO:0002098 - tRNA wobble uridine modification
GO:0002926 - tRNA wobble base 5-methoxycarbonylmethyl-2-thiouridinylation
GO:0005506 - iron ion binding
GO:0005634 - nucleus
GO:0005737 - cytoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

726282

ATS1
Protein KTI13

8

2

Small-scale

0.977

High

825369

DPH1
2-(3-amino-3-carboxypropyl)histidine synthase subunit 1

8

2

Small-scale

0.745

High

737151

DPH2
2-(3-amino-3-carboxypropyl)histidine synthase subunit 2

5

2

Small-scale

0.706

High

1039701

ELP3
Elongator complex protein 3

5

0

Small-scale

0.683

High

844360

ELP2
Elongator complex protein 2

5

0

Small-scale

0.680

High

1056581

ELP1
Elongator complex protein 1

5

0

Small-scale

0.673

High

734245

EF2
Elongation factor 2

2

0

Small-scale

0.576

High

801188

SIC1
Protein SIC1

1

0

High-throughput

0.518

High

672370

RV161
Reduced viability upon starvation protein 161

1

1

High-throughput

0.515

High

814322

RV167
Reduced viability upon starvation protein 167

1

1

High-throughput

0.515

High

744032

RAD23
UV excision repair protein RAD23

1

0

High-throughput

0.493

High

826131

ULP2
Ubiquitin-like-specific protease 2

1

0

High-throughput

0.460

High

361982

HIS1
ATP phosphoribosyltransferase

1

0

High-throughput

0.458

High

455344

RS19A
Small ribosomal subunit protein eS19A

1

0

Small-scale

0.458

High

661836

TOM40
Mitochondrial import receptor subunit TOM40

1

0

Small-scale

0.458

High

689747

RS7A
Small ribosomal subunit protein eS7A

1

0

Small-scale

0.458

High

709501

HRR25
Casein kinase I homolog HRR25

1

0

Small-scale

0.458

High

758528

KTI12
Protein KTI12

1

0

High-throughput

0.458

High

800928

NCB5R
NADH-cytochrome b5 reductase 1

1

0

Small-scale

0.458

High

806411

ELP5
Elongator complex protein 5

1

0

Small-scale

0.458

High

481829

HSP73
Heat shock protein SSA3

1

2

High-throughput

0.445

High

510943

HSP77
Import motor subunit, mitochondrial

1

1

High-throughput

0.445

High

525704

HSP71
Heat shock protein SSA1

1

2

High-throughput

0.445

High

528145

HSP72
Heat shock protein SSA2

1

2

High-throughput

0.445

High

546924

SSB1
Ribosome-associated molecular chaperone SSB1

1

2

High-throughput

0.445

High

671291

SIS1
Protein SIS1

1

1

High-throughput

0.445

High

811447

CAJ1
Protein CAJ1

1

2

High-throughput

0.445

High

816494

HSP7E
Heat shock protein SSC3, mitochondrial

1

1

High-throughput

0.445

High

820241

SSB2
Ribosome-associated molecular chaperone SSB2

1

2

High-throughput

0.445

High

826519

DJP1
DnaJ-like protein 1

1

2

High-throughput

0.445

High

676512

MAS5
Mitochondrial protein import protein MAS5

1

0

High-throughput

0.426

High

752941

HSP78
Heat shock protein 78, mitochondrial

1

0

High-throughput

0.426

High

1055174

CORO
Coronin-like protein

1

0

High-throughput

0.269

Low

432042

ATPF
ATP synthase subunit 4, mitochondrial

1

0

Small-scale

0.249

Low

835975

VATH
V-type proton ATPase subunit H

1

0

Small-scale

0.249

Low

1064866

RRS1
Regulator of ribosome biosynthesis

1

0

Small-scale

0.249

Low

918092

JAC1
J-type co-chaperone JAC1, mitochondrial

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025