Protein: RFA2
Replication factor A protein 2 (RF-A protein 2) (DNA-binding protein BUF1) (Replication protein A 36 kDa subunit)

Gene: RFA2
Organism: Saccharomyces cerevisiae S288C
Interactions: 79
UniProt ID: P26754

Gene Ontology (top 5):
GO:0000723 - telomere maintenance
GO:0000722 - telomere maintenance via recombination
GO:0000724 - double-strand break repair via homologous recombination
GO:0000781 - chromosome, telomeric region
GO:0000794 - condensed nuclear chromosome

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

607216

RFA1
Replication factor A protein 1

17

9

Small-scale

0.986

High

644733

RFA3
Replication factor A protein 3

10

0

Small-scale

0.924

High

644752

ATR
Serine/threonine-protein kinase MEC1

9

10

Small-scale

0.755

High

419601

RAD52
DNA repair and recombination protein RAD52

7

3

Small-scale

0.746

High

644754

DNA2
DNA replication ATP-dependent helicase/nuclease DNA2 [Includes: DNA replication nuclease DNA2

3

3

Small-scale

0.656

High

632515

DMC1
Meiotic recombination protein DMC1

2

5

Small-scale

0.629

High

644732

RFA2
Replication factor A protein 2

1

3

Small-scale

0.621

High

355374

H2B1
Histone H2B.1

3

3

Small-scale

0.603

High

644769

SAE3
Pachytene arrest protein SAE3

2

0

Small-scale

0.603

High

392067

H2A1
Histone H2A.1

2

4

Small-scale

0.595

High

644774

LCD1
DNA damage checkpoint protein LCD1

2

0

High-throughput

0.576

High

543302

HSC82
ATP-dependent molecular chaperone HSC82

2

4

High-throughput

0.571

High

356285

H4
Histone H4

2

2

Small-scale

0.570

High

644768

H3
Histone H3

2

2

Small-scale

0.570

High

644772

MSH6
DNA mismatch repair protein MSH6

2

5

High-throughput

0.567

High

644785

CMR1
DNA damage-binding protein CMR1

2

6

High-throughput

0.558

High

644742

IME2
Meiosis induction protein kinase IME2/SME1

2

6

Small-scale

0.550

High

644740

MEI5
Meiosis protein 5

1

0

Small-scale

0.537

High

644762

MPH1
ATP-dependent DNA helicase MPH1

2

13

Small-scale

0.533

High

500604

RAD18
Postreplication repair E3 ubiquitin-protein ligase RAD18

1

2

Small-scale

0.527

High

644782

SIZ2
E3 SUMO-protein ligase SIZ2

1

4

Small-scale

0.527

High

644775

KU80
ATP-dependent DNA helicase II subunit 2

1

5

Small-scale

0.515

High

644744

MG101
Mitochondrial genome maintenance protein MGM101

1

0

High-throughput

0.513

High

644734

RAD14
DNA repair protein RAD14

1

2

Small-scale

0.512

High

632548

RAD51
DNA repair protein RAD51

1

5

Small-scale

0.501

High

644751

ATM
Serine/threonine-protein kinase TEL1

1

9

Small-scale

0.501

High

644745

CDC13
Cell division control protein 13

1

0

Small-scale

0.493

High

644778

TERT
Telomerase reverse transcriptase

1

0

Small-scale

0.493

High

629537

CDC10
Cell division control protein 10

1

4

High-throughput

0.489

High

644739

IF2G
Eukaryotic translation initiation factor 2 subunit gamma

1

6

High-throughput

0.489

High

392323

H2A2
Histone H2A.2

1

4

High-throughput

0.479

High

599959

RIR3
Ribonucleoside-diphosphate reductase large chain 2

1

1

High-throughput

0.479

High

628820

RAD57
DNA repair protein RAD57

1

5

Small-scale

0.479

High

644737

MCM4
DNA replication licensing factor MCM4

1

5

High-throughput

0.479

High

644738

RPC3
DNA-directed RNA polymerase III subunit RPC3

1

1

High-throughput

0.479

High

644741

SPT16
FACT complex subunit SPT16

1

3

Small-scale

0.479

High

644749

BDF1
Bromodomain-containing factor 1

1

3

Small-scale

0.479

High

644770

CTF4
DNA polymerase alpha-binding protein

1

7

Small-scale

0.479

High

644771

TOM1
E3 ubiquitin-protein ligase TOM1

1

3

High-throughput

0.479

High

644773

CAC2
Chromatin assembly factor 1 subunit p60

1

5

Small-scale

0.479

High

644783

RAD59
DNA repair protein RAD59

1

3

Small-scale

0.479

High

431348

LTE1
Guanine nucleotide exchange factor LTE1

1

2

High-throughput

0.470

High

644763

RSC8
Chromatin structure-remodeling complex protein RSC8

1

1

High-throughput

0.470

High

644760

RT106
Histone chaperone RTT106

1

0

Small-scale

0.458

High

644784

PSY3
Platinum sensitivity protein 3

1

0

Small-scale

0.458

High

644764

DPB11
DNA replication regulator DPB11

1

2

Small-scale

0.457

High

644747

SGS1
ATP-dependent helicase SGS1

1

13

Small-scale

0.457

High

341949

ATPB
ATP synthase subunit beta, mitochondrial

1

1

High-throughput

0.457

High

630773

STDH
Catabolic L-serine/threonine dehydratase [Includes: L-serine dehydratase

1

2

High-throughput

0.457

High

644748

MDJ1
DnaJ homolog 1, mitochondrial

1

1

High-throughput

0.457

High

644765

TCPQ
T-complex protein 1 subunit theta

1

7

High-throughput

0.457

High

644767

ALDH6
Magnesium-activated aldehyde dehydrogenase, cytosolic

1

3

High-throughput

0.457

High

355806

H2B2
Histone H2B.2

1

3

High-throughput

0.437

High

365893

HSP82
ATP-dependent molecular chaperone HSP82

1

4

High-throughput

0.437

High

615120

BUR1
Serine/threonine-protein kinase BUR1

1

9

Small-scale

0.437

High

644735

TF2B
Transcription initiation factor IIB

1

2

High-throughput

0.437

High

644736

TF3B
Transcription factor IIIB 70 kDa subunit

1

2

High-throughput

0.437

High

644753

DPOA2
DNA polymerase alpha subunit B

1

1

High-throughput

0.437

High

644756

IF4F1
Eukaryotic initiation factor 4F subunit p150

1

2

High-throughput

0.437

High

644777

IMB1
Importin subunit beta-1

1

6

Small-scale

0.437

High

644780

VAM6
Vacuolar morphogenesis protein 6

1

1

High-throughput

0.437

High

490502

HSP71
Heat shock protein SSA1

1

2

High-throughput

0.407

High

493339

HSP72
Heat shock protein SSA2

1

2

High-throughput

0.407

High

510456

SSB1
Ribosome-associated molecular chaperone SSB1

1

2

High-throughput

0.407

High

627748

SIS1
Protein SIS1

1

3

High-throughput

0.407

High

644743

HSP7F
Heat shock protein homolog SSE1

1

6

High-throughput

0.407

High

644757

HSP7E
Heat shock protein SSC3, mitochondrial

1

4

High-throughput

0.407

High

644759

SSB2
Ribosome-associated molecular chaperone SSB2

1

2

High-throughput

0.407

High

644761

JEM1
DnaJ-like chaperone JEM1

1

3

High-throughput

0.407

High

644758

RT105
Regulator of Ty1 transposition protein 105

2

0

Small-scale

0.340

High

612203

HSP12
12 kDa heat shock protein

2

0

High-throughput

0.307

High

644750

AHP1
Peroxiredoxin AHP1

1

0

High-throughput

0.279

Low

644766

HIR3
Histone transcription regulator 3

1

0

High-throughput

0.279

Low

644755

MNL1
ER degradation-enhancing alpha-mannosidase-like protein 1

1

0

High-throughput

0.269

Low

644776

BUR2
Protein BUR2

1

0

Small-scale

0.249

Low

644779

TFC6
Transcription factor tau 91 kDa subunit

1

0

High-throughput

0.249

Low

644781

YL11B
Transposon Ty1-LR1 Gag-Pol polyprotein

1

0

High-throughput

0.249

Low

644746

HSP78
Heat shock protein 78, mitochondrial

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024