HitPredict - High confidence protein-protein interactions

Interactor 1: ESM8 (P13098)
Enhancer of split m8 protein (E(spl)m8)
Gene: E(spl)m8-HLH

Interactor 2: ESM8 (P13098)
Enhancer of split m8 protein (E(spl)m8)
Gene: E(spl)m8-HLH

Species: Drosophila melanogaster

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.59	1.00	0.768

Property	Details
Experiments	21789514, 9371806
Identification Methods	two hybrid
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	Hairy_orange~Hairy_orange, HLH~HLH
Common GO terms	GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific GO:0001227 - DNA-binding transcription repressor activity, RNA polymerase II-specific GO:0005634 - nucleus GO:0006357 - regulation of transcription by RNA polymerase II and 10 others more... GO:0007498 - mesoderm development GO:0009952 - anterior/posterior pattern specification GO:0010629 - negative regulation of gene expression GO:0016360 - sensory organ precursor cell fate determination GO:0042803 - protein homodimerization activity GO:0043565 - sequence-specific DNA binding GO:0046982 - protein heterodimerization activity GO:0048749 - compound eye development GO:0048813 - dendrite morphogenesis GO:0050767 - regulation of neurogenesis
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1	179
Dm

1	179

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Last updated: 15 Jul 2024