Protein: AK
Aspartokinase (EC 2.7.2.4) (Aspartate kinase)

Gene: AK, HOM3
Organism: Saccharomyces cerevisiae S288C
Interactions: 38
UniProt ID: P10869

Gene Ontology (top 5):
GO:0004072 - aspartate kinase activity
GO:0005524 - ATP binding
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0009086 - methionine biosynthetic process

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

533502

AK
Aspartokinase

2

5

Small-scale

0.767

High

533506

FKBP
FK506-binding protein 1

6

1

Small-scale

0.738

High

533524

RPN11
Ubiquitin carboxyl-terminal hydrolase RPN11

2

1

High-throughput

0.584

High

533503

SSB1
Ribosome-associated molecular chaperone SSB1

2

1

High-throughput

0.552

High

533516

RIM11
Serine/threonine-protein kinase RIM11/MSD1

1

1

High-throughput

0.536

High

416848

CDC25
Cell division control protein 25

1

0

High-throughput

0.518

High

454379

PHO4
Phosphate system positive regulatory protein PHO4

1

0

High-throughput

0.513

High

533511

GSP1
GTP-binding nuclear protein GSP1/CNR1

1

0

High-throughput

0.513

High

533526

2ABA
Protein phosphatase PP2A regulatory subunit B

1

0

High-throughput

0.513

High

533530

RAD59
DNA repair protein RAD59

1

0

High-throughput

0.513

High

533525

BIT61
Target of rapamycin complex 2 subunit BIT61

1

0

High-throughput

0.486

High

392102

HSP82
ATP-dependent molecular chaperone HSP82

1

1

High-throughput

0.479

High

533504

HSC82
ATP-dependent molecular chaperone HSC82

1

1

High-throughput

0.479

High

533507

IF2A
Eukaryotic translation initiation factor 2 subunit alpha

1

1

High-throughput

0.479

High

533509

SIS1
Protein SIS1

1

1

High-throughput

0.479

High

533531

AP2M
AP-2 complex subunit mu

1

0

Small-scale

0.460

High

399331

CARB
Carbamoyl phosphate synthase arginine-specific large chain

1

0

High-throughput

0.458

High

486389

TBA3
Tubulin alpha-3 chain

1

0

High-throughput

0.458

High

533512

PRS6A
26S proteasome regulatory subunit 6A

1

0

High-throughput

0.458

High

533513

ADH5
Alcohol dehydrogenase 5

1

0

High-throughput

0.458

High

533515

ATG8
Autophagy-related protein 8

1

0

High-throughput

0.458

High

533517

RPN1
26S proteasome regulatory subunit RPN1

1

0

High-throughput

0.458

High

533518

RPN10
26S proteasome regulatory subunit RPN10

1

0

High-throughput

0.458

High

533523

RTS2
Zinc finger protein RTS2

1

0

High-throughput

0.458

High

533527

ESP1
Separin

1

0

High-throughput

0.458

High

522849

HSP71
Heat shock protein SSA1

1

1

High-throughput

0.445

High

525741

HSP72
Heat shock protein SSA2

1

1

High-throughput

0.445

High

533521

SSB2
Ribosome-associated molecular chaperone SSB2

1

1

High-throughput

0.445

High

533520

PCF11
Protein PCF11

1

0

High-throughput

0.438

High

533505

SPO16
Sporulation-specific protein 16

1

0

Small-scale

0.249

Low

533508

RPC2
DNA-directed RNA polymerase III subunit RPC2

1

0

High-throughput

0.249

Low

533510

TF2B
Transcription initiation factor IIB

1

0

High-throughput

0.249

Low

533514

NU170
Nucleoporin NUP170

1

0

High-throughput

0.249

Low

533519

GGC1
Mitochondrial GTP/GDP carrier protein 1

1

0

High-throughput

0.249

Low

533522

DSN1
Kinetochore-associated protein DSN1

1

0

High-throughput

0.249

Low

533528

NKP2
Inner kinetochore subunit NKP2

1

0

High-throughput

0.249

Low

533529

AP3D
AP-3 complex subunit delta

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025