Interactor 1: TOP3 (P13099)
DNA topoisomerase 3 (EC 5.6.2.1) (DNA topoisomerase III)
Gene: TOP3

Interactor 2: RMI1 (Q02685)
RecQ-mediated genome instability protein 1
Gene: RMI1

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.95 0.90 0.925

The method score is based on:

Property Details
Experiments 20811460, 24509834, 15899853, 15889139, 27298337, 31351878, 17693398, 36942481
Identification Methods pull down, affinity chromatography technology, biochemical, enzymatic study, anti tag coimmunoprecipitation
Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains RMI1_N~Topoisom_bac
Common GO terms GO:0000724 - double-strand break repair via homologous recombination
GO:0005634 - nucleus
GO:0006265 - DNA topological change
GO:0007064 - mitotic sister chromatid cohesion
GO:0031422 - RecQ family helicase-topoisomerase III complex
Homologous interactions 0

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024