Protein: SYEC
Glutamate--tRNA ligase, cytoplasmic (EC 6.1.1.17) (Glutamyl-tRNA synthetase) ((c)ERS) (GluRS) (P85)

Gene: SYEC, GUS1
Organism: Saccharomyces cerevisiae S288C
Interactions: 185
UniProt ID: P46655

Gene Ontology (top 5):
GO:0003729 - mRNA binding
GO:0004818 - glutamate-tRNA ligase activity
GO:0005524 - ATP binding
GO:0005737 - cytoplasm
GO:0005739 - mitochondrion

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

858102

ARC1
tRNA-aminoacylation cofactor ARC1

11

7

Small-scale

0.757

High

368907

SYMC
Methionine--tRNA ligase, cytoplasmic

5

9

Small-scale

0.712

High

579622

HSC82
ATP-dependent molecular chaperone HSC82

3

7

High-throughput

0.633

High

675344

RAD51
DNA repair protein RAD51

2

1

High-throughput

0.621

High

574702

KSS1
Mitogen-activated protein kinase KSS1

2

4

High-throughput

0.619

High

656805

KC12
Casein kinase I homolog 2

2

2

High-throughput

0.602

High

645947

DBF2
Cell cycle protein kinase DBF2

2

3

High-throughput

0.602

High

656521

KC11
Casein kinase I homolog 1

2

2

High-throughput

0.602

High

858153

DBP10
ATP-dependent RNA helicase DBP10

2

4

High-throughput

0.601

High

558781

CAF20
Cap-associated protein CAF20

2

1

High-throughput

0.584

High

727134

HS104
Heat shock protein 104

2

1

High-throughput

0.571

High

779075

EF1G2
Elongation factor 1-gamma 2

2

0

High-throughput

0.563

High

806969

2A5D
Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta isoform

2

0

High-throughput

0.563

High

815154

IF4F1
Eukaryotic initiation factor 4F subunit p150

2

0

High-throughput

0.559

High

506374

NFT1
ABC transporter NFT1

1

2

High-throughput

0.541

High

758009

PXA2
Peroxisomal long-chain fatty acid import protein 1

1

1

High-throughput

0.541

High

737328

CDC12
Cell division control protein 12

1

1

High-throughput

0.536

High

793430

ATR
Serine/threonine-protein kinase MEC1

1

1

High-throughput

0.536

High

797970

ATG12
Ubiquitin-like protein ATG12

1

1

High-throughput

0.536

High

858113

BRE5
UBP3-associated protein BRE5

1

2

High-throughput

0.536

High

858119

UBP3
Ubiquitin carboxyl-terminal hydrolase 3

1

1

High-throughput

0.536

High

858146

RTK1
Probable serine/threonine-protein kinase RTK1

1

3

High-throughput

0.536

High

858154

RUVB2
RuvB-like protein 2

1

1

High-throughput

0.536

High

826608

DSN1
Kinetochore-associated protein DSN1

2

1

High-throughput

0.533

High

704619

SBA1
Co-chaperone protein SBA1

1

1

Small-scale

0.527

High

795772

HEK2
Heterogeneous nuclear rnp K-like protein 2

1

1

High-throughput

0.515

High

805350

UBA4
Adenylyltransferase and sulfurtransferase UBA4

1

1

High-throughput

0.515

High

822456

TBP6
Probable 26S proteasome subunit YTA6

1

9

High-throughput

0.515

High

858143

LKHA4
Leucine aminopeptidase 2

1

2

High-throughput

0.515

High

533178

GPA2
Guanine nucleotide-binding protein alpha-2 subunit

1

0

High-throughput

0.513

High

644946

RPA2
DNA-directed RNA polymerase I subunit RPA135

1

0

High-throughput

0.513

High

822956

RFC4
Replication factor C subunit 4

1

0

High-throughput

0.513

High

836762

MPG1
Mannose-1-phosphate guanyltransferase

1

0

High-throughput

0.513

High

470145

SPS1
Sporulation-specific protein 1

1

1

High-throughput

0.501

High

642413

MCK1
Protein kinase MCK1

1

3

High-throughput

0.501

High

672194

KIN82
Serine/threonine-protein kinase KIN82

1

1

High-throughput

0.501

High

673710

KCC4
Probable serine/threonine-protein kinase KCC4

1

1

High-throughput

0.501

High

694148

CDC15
Cell division control protein 15

1

1

High-throughput

0.501

High

704686

PRR1
Serine/threonine-protein kinase PRR1

1

1

High-throughput

0.501

High

725925

PSK1
Serine/threonine-protein kinase PSK1

1

1

High-throughput

0.501

High

735520

IRE1
Serine/threonine-protein kinase/endoribonuclease IRE1

1

3

High-throughput

0.501

High

740586

IME2
Meiosis induction protein kinase IME2/SME1

1

5

High-throughput

0.501

High

800719

RCK1
Serine/threonine-protein kinase RCK1

1

3

High-throughput

0.501

High

801861

KSP1
Serine/threonine-protein kinase KSP1

1

3

High-throughput

0.501

High

815484

RSP5
E3 ubiquitin-protein ligase RSP5

1

7

High-throughput

0.501

High

858103

IKS1
Probable serine/threonine-protein kinase IKS1

1

1

High-throughput

0.501

High

858118

BCK1
Serine/threonine-protein kinase BCK1/SLK1/SSP31

1

2

High-throughput

0.501

High

858121

FRK1
Fatty acyl-CoA synthetase and RNA processing-associated kinase 1

1

2

High-throughput

0.501

High

858124

STE20
Serine/threonine-protein kinase STE20

1

4

High-throughput

0.501

High

858155

SKM1
Serine/threonine-protein kinase SKM1

1

4

High-throughput

0.501

High

858156

SKS1
Serine/threonine-protein kinase SKS1

1

2

High-throughput

0.501

High

617406

GBB
Guanine nucleotide-binding protein subunit beta

1

3

High-throughput

0.500

High

628078

FKBP
FK506-binding protein 1

1

1

High-throughput

0.500

High

743247

PP12
Serine/threonine-protein phosphatase PP1-2

1

2

High-throughput

0.500

High

858136

SHS1
Seventh homolog of septin 1

1

2

High-throughput

0.500

High

758507

SLD2
DNA replication regulator SLD2

1

0

High-throughput

0.493

High

782580

DAD2
DASH complex subunit DAD2

1

0

High-throughput

0.493

High

825830

YRB2
Ran-specific GTPase-activating protein 2

1

0

High-throughput

0.493

High

844373

ETFB
Probable electron transfer flavoprotein subunit beta

1

0

High-throughput

0.493

High

845894

UAP1
UDP-N-acetylglucosamine pyrophosphorylase

1

0

High-throughput

0.493

High

858128

CSM3
Chromosome segregation in meiosis protein 3

1

0

High-throughput

0.493

High

858142

YIG1
Protein YIG1

1

0

High-throughput

0.493

High

858145

SLX4
Structure-specific endonuclease subunit SLX4

1

0

High-throughput

0.493

High

858148

YP245
Uncharacterized protein YPL245W

1

0

High-throughput

0.493

High

858149

POC4
Proteasome chaperone 4

1

0

High-throughput

0.493

High

858129

ERB1
Ribosome biogenesis protein ERB1

1

3

High-throughput

0.489

High

506395

YK104
Putative uncharacterized protein YKR104W

1

1

High-throughput

0.481

High

646446

RAD53
Serine/threonine-protein kinase RAD53

1

0

High-throughput

0.480

High

825406

PRK1
Actin-regulating kinase PRK1

1

0

High-throughput

0.480

High

536139

ARF1
ADP-ribosylation factor 1

1

0

High-throughput

0.479

High

738665

EI2BB
Translation initiation factor eIF2B subunit beta

1

0

High-throughput

0.479

High

858117

RHO4
GTP-binding protein RHO4

1

0

High-throughput

0.479

High

364605

CDK1
Cyclin-dependent kinase 1

1

3

High-throughput

0.479

High

392940

HSP82
ATP-dependent molecular chaperone HSP82

1

7

High-throughput

0.479

High

416256

SYDC
Aspartate--tRNA ligase, cytoplasmic

1

14

High-throughput

0.479

High

435182

RS3
Small ribosomal subunit protein uS3

1

1

High-throughput

0.479

High

464612

PBS2
MAP kinase kinase PBS2

1

1

High-throughput

0.479

High

511340

RL43A
Large ribosomal subunit protein eL43A

1

1

High-throughput

0.479

High

511442

RL43B
Large ribosomal subunit protein eL43B

1

1

High-throughput

0.479

High

513520

RL1A
Large ribosomal subunit protein uL1A

1

1

High-throughput

0.479

High

581877

SYKC
Lysine--tRNA ligase, cytoplasmic

1

14

High-throughput

0.479

High

649639

KCC2
Calcium/calmodulin-dependent protein kinase II

1

2

High-throughput

0.479

High

670864

SIS1
Protein SIS1

1

2

High-throughput

0.479

High

678783

PDP2
[Pyruvate dehydrogenase [acetyl-transferring]]-phosphatase 2, mitochondrial

1

1

High-throughput

0.479

High

679819

CDC48
Cell division control protein 48

1

3

High-throughput

0.479

High

689528

RS7A
Small ribosomal subunit protein eS7A

1

1

High-throughput

0.479

High

709843

BMH1
Protein BMH1

1

4

High-throughput

0.479

High

737893

HOG1
Mitogen-activated protein kinase HOG1

1

3

High-throughput

0.479

High

746519

HFA1
Acetyl-CoA carboxylase, mitochondrial

1

2

High-throughput

0.479

High

783484

SYYC
Tyrosine--tRNA ligase, cytoplasmic

1

2

High-throughput

0.479

High

785937

LONM
Lon protease homolog, mitochondrial

1

8

High-throughput

0.479

High

792114

GBLP
Small ribosomal subunit protein RACK1

1

4

High-throughput

0.479

High

802566

SYNC
Asparagine--tRNA ligase, cytoplasmic

1

14

High-throughput

0.479

High

802648

YHI0
Putative proline--tRNA ligase YHR020W

1

6

High-throughput

0.479

High

812068

DHH1
ATP-dependent RNA helicase DHH1

1

3

High-throughput

0.479

High

824904

TM108
Protein TMA108

1

2

High-throughput

0.479

High

850064

RPN11
Ubiquitin carboxyl-terminal hydrolase RPN11

1

2

High-throughput

0.479

High

858109

PIL1
Sphingolipid long chain base-responsive protein PIL1

1

1

High-throughput

0.479

High

858112

PPID
Peptidyl-prolyl cis-trans isomerase CPR6

1

3

High-throughput

0.479

High

858122

TOM1
E3 ubiquitin-protein ligase TOM1

1

7

High-throughput

0.479

High

858126

RUVB1
RuvB-like protein 1

1

1

High-throughput

0.479

High

858158

SMC6
Structural maintenance of chromosomes protein 6

1

1

High-throughput

0.479

High

548216

BIK1
Nuclear fusion protein BIK1

1

1

High-throughput

0.470

High

858157

H2AZ
Histone H2A.Z

1

3

High-throughput

0.470

High

858107

SC6B1
Protein transport protein SBH1

1

0

Small-scale

0.460

High

149831

RS9A
Small ribosomal subunit protein uS4A

1

0

High-throughput

0.458

High

383767

RS17A
Small ribosomal subunit protein eS17A

1

0

High-throughput

0.458

High

410202

RL25
Large ribosomal subunit protein uL23

1

0

High-throughput

0.458

High

433709

RL26A
Large ribosomal subunit protein uL24A

1

0

High-throughput

0.458

High

434040

RL33A
Large ribosomal subunit protein eL33A

1

0

High-throughput

0.458

High

436033

RS13
Small ribosomal subunit protein uS15

1

0

High-throughput

0.458

High

441985

RS14A
Small ribosomal subunit protein uS11A

1

0

High-throughput

0.458

High

455128

RS19A
Small ribosomal subunit protein eS19A

1

0

High-throughput

0.458

High

503113

RS22A
Small ribosomal subunit protein uS8A

1

0

High-throughput

0.458

High

504280

RL31A
Large ribosomal subunit protein eL31A

1

0

High-throughput

0.458

High

512509

RS6A
Small ribosomal subunit protein eS6A

1

0

High-throughput

0.458

High

513081

RS8A
Small ribosomal subunit protein eS8A

1

0

High-throughput

0.458

High

514697

RS18A
Small ribosomal subunit protein uS13A

1

0

High-throughput

0.458

High

577375

MTF1
Mitochondrial transcription factor 1

1

0

High-throughput

0.458

High

674695

RS2
Small ribosomal subunit protein uS5

1

0

High-throughput

0.458

High

747440

RSSA1
Small ribosomal subunit protein uS2A

1

0

High-throughput

0.458

High

747921

SMY2
Protein SMY2

1

0

High-throughput

0.458

High

753442

RS3A1
Small ribosomal subunit protein eS1A

1

0

High-throughput

0.458

High

778394

RS27A
Small ribosomal subunit protein eS27A

1

0

High-throughput

0.458

High

797754

AIM4
Altered inheritance of mitochondria protein 4

1

0

High-throughput

0.458

High

802242

RS20
Small ribosomal subunit protein uS10

1

0

High-throughput

0.458

High

812428

LAA1
AP-1 accessory protein LAA1

1

0

High-throughput

0.458

High

818542

YEY6
MYG1 protein YER156C

1

0

Small-scale

0.458

High

825797

FIS1
Mitochondrial fission 1 protein

1

0

Small-scale

0.458

High

827538

RLP7
Ribosome biogenesis protein RLP7

1

0

High-throughput

0.458

High

858104

RS12
Small ribosomal subunit protein eS12

1

0

High-throughput

0.458

High

858110

PESC
Pescadillo homolog

1

0

High-throughput

0.458

High

858111

YG2W
Uncharacterized protein YGR111W

1

0

High-throughput

0.458

High

858116

SAM50
Sorting assembly machinery 50 kDa subunit

1

0

High-throughput

0.458

High

858120

RS15
Small ribosomal subunit protein uS19

1

0

High-throughput

0.458

High

858137

SGO1
Shugoshin

1

0

High-throughput

0.458

High

858138

MCA1
Metacaspase-1

1

0

High-throughput

0.458

High

858140

RS10A
Small ribosomal subunit protein eS10A

1

0

High-throughput

0.458

High

822256

DOA10
ERAD-associated E3 ubiquitin-protein ligase DOA10

1

1

High-throughput

0.457

High

625024

PRP6
Pre-mRNA-splicing factor 6

1

2

High-throughput

0.457

High

748185

SUI1
Eukaryotic translation initiation factor eIF-1

1

1

High-throughput

0.457

High

368347

TRPG
Multifunctional tryptophan biosynthesis protein [Includes: Anthranilate synthase component 2

1

1

High-throughput

0.445

High

524346

HSP71
Heat shock protein SSA1

1

6

High-throughput

0.445

High

545334

SSB1
Ribosome-associated molecular chaperone SSB1

1

6

High-throughput

0.445

High

692384

KCC1
Calcium/calmodulin-dependent protein kinase I

1

1

High-throughput

0.445

High

804251

SSZ1
Ribosome-associated complex subunit SSZ1

1

4

High-throughput

0.445

High

819093

SSB2
Ribosome-associated molecular chaperone SSB2

1

6

High-throughput

0.445

High

825453

LYS12
Homoisocitrate dehydrogenase, mitochondrial

1

2

High-throughput

0.445

High

858115

APJ1
J domain-containing protein APJ1

1

1

High-throughput

0.445

High

707456

TF2B
Transcription initiation factor IIB

1

1

High-throughput

0.437

High

858125

YMC0
Uncharacterized protein YML020W

1

1

High-throughput

0.437

High

858127

POB3
FACT complex subunit POB3

1

1

High-throughput

0.437

High

858141

AP3D
AP-3 complex subunit delta

1

2

High-throughput

0.437

High

858147

RRP6
Exosome complex exonuclease RRP6

1

2

High-throughput

0.437

High

480516

PUT1
Proline dehydrogenase, mitochondrial

1

0

High-throughput

0.426

High

566511

DHAS
Aspartate-semialdehyde dehydrogenase

1

0

High-throughput

0.426

High

779423

MAOM
NAD-dependent malic enzyme, mitochondrial

1

0

High-throughput

0.426

High

782265

DRE2
Fe-S cluster assembly protein DRE2

1

0

High-throughput

0.426

High

858106

PFD6
Prefoldin subunit 6

1

0

High-throughput

0.426

High

858152

UTP23
rRNA-processing protein UTP23

1

0

High-throughput

0.426

High

459118

RPAC1
DNA-directed RNA polymerases I and III subunit RPAC1

1

0

High-throughput

0.279

Low

808518

TEM1
Protein TEM1

1

0

High-throughput

0.279

Low

858130

SEN15
tRNA-splicing endonuclease subunit SEN15

1

0

High-throughput

0.279

Low

676814

BUD3
Bud site selection protein 3

1

0

High-throughput

0.269

Low

754701

PMT1
Dolichyl-phosphate-mannose--protein mannosyltransferase 1

1

0

High-throughput

0.269

Low

777198

PPAB
Acid phosphatase PHO11

1

0

High-throughput

0.269

Low

858123

DIG2
Down-regulator of invasive growth 2

1

0

High-throughput

0.269

Low

858144

TGL5
Triacylglycerol lipase 5

1

0

High-throughput

0.269

Low

858151

YOR97
Uncharacterized protein YOR097C

1

0

High-throughput

0.269

Low

750268

PRP40
Pre-mRNA-processing protein PRP40

1

0

High-throughput

0.261

Low

763929

SPT10
Protein SPT10

1

0

High-throughput

0.249

Low

764105

SPT21
Protein SPT21

1

0

High-throughput

0.249

Low

795065

NU170
Nucleoporin NUP170

1

0

High-throughput

0.249

Low

807820

SSN2
Mediator of RNA polymerase II transcription subunit 13

1

0

Small-scale

0.249

Low

858105

VATG
V-type proton ATPase subunit G

1

0

High-throughput

0.249

Low

858108

ERV14
ER-derived vesicles protein ERV14

1

0

High-throughput

0.249

Low

858131

DPP1
Diacylglycerol pyrophosphate phosphatase 1

1

0

High-throughput

0.249

Low

858132

MMS22
E3 ubiquitin-protein ligase substrate receptor MMS22

1

0

High-throughput

0.249

Low

858133

SEC10
Exocyst complex component SEC10

1

0

Small-scale

0.249

Low

858134

TFC6
Transcription factor tau 91 kDa subunit

1

0

High-throughput

0.249

Low

858135

URN1
Pre-mRNA-splicing factor URN1

1

0

High-throughput

0.249

Low

858139

ESA1
Histone acetyltransferase ESA1

1

0

Small-scale

0.249

Low

483788

SWI1
SWI/SNF chromatin-remodeling complex subunit SWI1

1

0

High-throughput

0.232

Low

858114

NAF1
H/ACA ribonucleoprotein complex non-core subunit NAF1

1

0

High-throughput

0.232

Low

858150

CENPH
Inner kinetochore subunit MCM16

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025