Interactor 1: HEM1 (P13196)
5-aminolevulinate synthase, non-specific, mitochondrial (ALAS-H) (EC 2.3.1.37) (5-aminolevulinic acid synthase 1) (Delta-ALA synthase 1) (Delta-aminolevulinate synthase 1)
Gene: ALAS1
Interactor 2: HEM1 (P13196)
5-aminolevulinate synthase, non-specific, mitochondrial (ALAS-H) (EC 2.3.1.37) (5-aminolevulinic acid synthase 1) (Delta-ALA synthase 1) (Delta-aminolevulinate synthase 1)
Gene: ALAS1
Species: Homo sapiens
Source: intact
Category: High-throughput
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.74 | 1.00 | 0.861 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 25416956, 32296183, unassigned1304 |
| Identification Methods | two hybrid, two hybrid array, two hybrid prey pooling approach, validated two hybrid |
| Interaction Type | direct interaction, physical association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | Aminotran_1_2~Aminotran_1_2 |
| Common GO terms | GO:0003870 - 5-aminolevulinate synthase activity GO:0005654 - nucleoplasm GO:0005739 - mitochondrion GO:0005743 - mitochondrial inner membrane GO:0005759 - mitochondrial matrix and 10 others more... |
| Homologous interactions | 14 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
