Interactor 1: DPOLA (P13382)
DNA polymerase alpha catalytic subunit A (EC 2.7.7.7) (DNA polymerase I subunit A) (DNA polymerase alpha:primase complex p180 subunit) (DNA polymerase-primase complex p180 subunit) (Pol alpha-primase complex p180 subunit)
Gene: POL1

Interactor 2: MCM3 (P24279)
DNA replication licensing factor MCM3 (EC 3.6.4.12) (Minichromosome maintenance protein 3)
Gene: MCM3

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.71 0.60 0.656

The method score is based on:

Property Details
Experiments 24805245, 32075754, 32585006
Identification Methods anti tag coimmunoprecipitation, affinity chromatography technology
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0003682 - chromatin binding
GO:0003688 - DNA replication origin binding
GO:0003697 - single-stranded DNA binding
GO:0006270 - DNA replication initiation
GO:0006279 - premeiotic DNA replication
and 1 others

more...

Homologous interactions 10

Homologous interactions

Color coding for hit scores

1 1468
Sc

1 971
+ Sc
+ Sc
+ Hs
+ Sc
+ Hs
+ Sc
+ Sp
+ Sc
+ Sc
+ Sc

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Last updated: 15 Jul 2024