Interactor 1: DPOLA (P13382)
DNA polymerase alpha catalytic subunit A (EC 2.7.7.7) (DNA polymerase I subunit A) (DNA polymerase alpha:primase complex p180 subunit) (DNA polymerase-primase complex p180 subunit) (Pol alpha-primase complex p180 subunit)
Gene: POL1

Interactor 2: MCM2 (P29469)
DNA replication licensing factor MCM2 (EC 3.6.4.12) (Minichromosome maintenance protein 2)
Gene: MCM2

Species: Saccharomyces cerevisiae S288C

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.69 0.60 0.646

The method score is based on:

Property Details
Experiments 30104407, 28510759, 19496828
Identification Methods affinity chromatography technology, pull down
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0003682 - chromatin binding
GO:0003688 - DNA replication origin binding
GO:0003697 - single-stranded DNA binding
GO:0006279 - premeiotic DNA replication
GO:0046872 - metal ion binding
and 1 others

more...

Homologous interactions 10

Homologous interactions

Color coding for hit scores

1 1468
Sc

1 868
+ Hs
+ Sc
+ Sc
+ Sc
+ Sp
+ Sc
+ Sc
+ Sp
+ Sc
+ Sc

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024