HitPredict - High confidence protein-protein interactions

Interactor 1: TBP (P13393)
TATA-box-binding protein (TATA sequence-binding protein) (TBP) (TATA-binding factor) (TATA-box factor) (Transcription factor D) (Transcription initiation factor TFIID TBP subunit)
Gene: SPT15

Interactor 2: TBP (P13393)
TATA-box-binding protein (TATA sequence-binding protein) (TBP) (TATA-binding factor) (TATA-box factor) (Transcription factor D) (Transcription initiation factor TFIID TBP subunit)
Gene: SPT15

Species: Saccharomyces cerevisiae S288C

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.73	1.00	0.858

Property	Details
Experiments	10788514, 14534318, 17683121
Identification Methods	affinity chromatography technology, two hybrid, pull down
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	TBP~TBP
Common GO terms	GO:0000126 - transcription factor TFIIIB complex GO:0000979 - RNA polymerase II core promoter sequence-specific DNA binding GO:0001016 - RNA polymerase III transcription regulatory region sequence-specific DNA binding GO:0001092 - TFIIA-class transcription factor complex binding GO:0001179 - RNA polymerase I general transcription initiation factor binding and 20 others more... GO:0001188 - RNA polymerase I preinitiation complex assembly GO:0003682 - chromatin binding GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005667 - transcription regulator complex GO:0005669 - transcription factor TFIID complex GO:0005672 - transcription factor TFIIA complex GO:0006352 - DNA-templated transcription initiation GO:0006359 - regulation of transcription by RNA polymerase III GO:0008301 - DNA binding, bending GO:0016251 - RNA polymerase II general transcription initiation factor activity GO:0032991 - protein-containing complex GO:0042790 - nucleolar large rRNA transcription by RNA polymerase I GO:0045892 - negative regulation of DNA-templated transcription GO:0045944 - positive regulation of transcription by RNA polymerase II GO:0051123 - RNA polymerase II preinitiation complex assembly GO:0061629 - RNA polymerase II-specific DNA-binding transcription factor binding GO:0070898 - RNA polymerase III preinitiation complex assembly GO:0097718 - disordered domain specific binding GO:0140297 - DNA-binding transcription factor binding
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1	240
Sc

1	240

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Last updated: 15 Jul 2024