HitPredict

Interactor 1: RB (P13405)
Retinoblastoma-associated protein (p110-RB1) (pRb) (Rb) (pp105)
Gene: Rb1

Interactor 2: CDK6 (Q64261)
Cyclin-dependent kinase 6 (EC 2.7.11.22) (CR2 protein kinase) (CRK2) (Cell division protein kinase 6) (Serine/threonine-protein kinase PLSTIRE)
Gene: CDK6

Species: Mus musculus

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.41 0.60 0.501

The method score is based on:

Property Details
Experiments 11254678
Identification Methods enzymatic study
Interaction Type direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000082 - G1/S transition of mitotic cell cycle
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0045786 - negative regulation of cell cycle
and 2 others

more...
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 921
Mm

1 326
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024