Protein: S12A1
Solute carrier family 12 member 1 (Bumetanide-sensitive sodium-(potassium)-chloride cotransporter 1) (BSC1) (Kidney-specific Na-K-Cl symporter) (Na-K-2Cl cotransporter 2) (NKCC2)

Gene: S12A1, SLC12A1
Organism: Homo sapiens
Interactions: 19
UniProt ID: Q13621

Gene Ontology (top 5):
GO:0005886 - plasma membrane
GO:0006811 - monoatomic ion transport
GO:0006884 - cell volume homeostasis
GO:0008511 - sodium:potassium:chloride symporter activity
GO:0016020 - membrane

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

343593

OXSR1
Serine/threonine-protein kinase OSR1

1

11

High-throughput

0.501

High

650747

ROA2
Heterogeneous nuclear ribonucleoproteins A2/B1

1

0

High-throughput

0.458

High

761395

HS71L
Heat shock 70 kDa protein 1-like

1

13

High-throughput

0.445

High

761673

HSP74
Heat shock 70 kDa protein 4

1

20

High-throughput

0.445

High

899031

TCPQ
T-complex protein 1 subunit theta

1

1

High-throughput

0.445

High

1115500

MIB1
E3 ubiquitin-protein ligase MIB1

1

1

High-throughput

0.445

High

1115501

DJC10
DnaJ homolog subfamily C member 10

1

4

High-throughput

0.445

High

1115502

HS105
Heat shock protein 105 kDa

1

20

High-throughput

0.445

High

1115503

DNJC7
DnaJ homolog subfamily C member 7

1

16

High-throughput

0.445

High

1115506

STK39
STE20/SPS1-related proline-alanine-rich protein kinase

1

10

High-throughput

0.445

High

1115507

BAG5
BAG family molecular chaperone regulator 5

1

9

High-throughput

0.445

High

1115505

UBP40
Ubiquitin carboxyl-terminal hydrolase 40

1

3

Small-scale

0.439

High

51279

ELOV7
Very long chain fatty acid elongase 7

1

9

High-throughput

0.407

High

343944

HS74L
Heat shock 70 kDa protein 4L

1

20

High-throughput

0.407

High

731272

STIP1
Stress-induced-phosphoprotein 1

1

11

High-throughput

0.407

High

1115508

CHIP
E3 ubiquitin-protein ligase CHIP

1

6

High-throughput

0.407

High

1115504

KT3K
Ketosamine-3-kinase

1

0

High-throughput

0.232

Low

1115509

TDRKH
Tudor and KH domain-containing protein

1

0

High-throughput

0.232

Low

1115510

RBGP1
Rab GTPase-activating protein 1

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025