HitPredict

Interactor 1: LAMP2 (P13473)
Lysosome-associated membrane glycoprotein 2 (LAMP-2) (Lysosome-associated membrane protein 2) (CD107 antigen-like family member B) (LGP-96) (CD antigen CD107b)
Gene: LAMP2

Interactor 2: DSC2 (Q02487)
Desmocollin-2 (Cadherin family member 2) (Desmocollin-3) (Desmosomal glycoprotein II) (Desmosomal glycoprotein III)
Gene: DSC2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	34079125
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0009267 - cellular response to starvation GO:0070062 - extracellular exosome
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 410 Hs			1 901
+	Hs
		506975 LAMP1_HUMAN (26-410): 3.76e-155: 446: 34.43		DSC2_HUMAN (1-901): 0: 855: 100.00
+	Hs
		507019 LAMP1_HUMAN (26-410): 3.76e-155: 446: 34.43		DSC3_HUMAN (1-901): 0: 806: 66.70
+	Hs
		527449 LAMP2_HUMAN (1-410): 0: 557: 100.00		DSG2_HUMAN (69-401): 2e-20: 99.3: 17.18
+	Hs
		506873 LAMP1_HUMAN (26-410): 3.76e-155: 446: 34.43		CADH2_HUMAN (4-385): 1.04e-51: 197: 15.55
+	Hs
		507013 LAMP1_HUMAN (26-410): 3.76e-155: 446: 34.43		DSG2_HUMAN (69-401): 2e-20: 99.3: 17.18
+	Hs
		1048685 LAMP3_HUMAN (155-410): 7.26e-75: 240: 25.95		DSG2_HUMAN (69-401): 2e-20: 99.3: 17.18