HitPredict

Interactor 1: LAMP2 (P13473)
Lysosome-associated membrane glycoprotein 2 (LAMP-2) (Lysosome-associated membrane protein 2) (CD107 antigen-like family member B) (LGP-96) (CD antigen CD107b)
Gene: LAMP2

Interactor 2: ROCK1 (Q13464)
Rho-associated protein kinase 1 (EC 2.7.11.1) (Renal carcinoma antigen NY-REN-35) (Rho-associated, coiled-coil-containing protein kinase 1) (Rho-associated, coiled-coil-containing protein kinase I) (ROCK-I) (p160 ROCK-1) (p160ROCK)
Gene: ROCK1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	34079125
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 410 Hs			1 1354
+	Hs
		507004 LAMP1_HUMAN (26-410): 3.76e-155: 446: 34.43		ROCK1_HUMAN (1-1354): 0: 886: 100.00
+	Hs
		254443 LAMP2_HUMAN (1-410): 0: 557: 100.00		ROCK2_HUMAN (7-1344): 0: 714: 64.97
+	Hs
		254441 LAMP1_HUMAN (26-410): 3.76e-155: 446: 34.43		ROCK2_HUMAN (7-1344): 0: 714: 64.97
+	Hs
		1035218 LAMP3_HUMAN (155-410): 7.26e-75: 240: 25.95		ROCK1_HUMAN (1-1354): 0: 886: 100.00
+	Hs
		254525 LAMP3_HUMAN (155-410): 7.26e-75: 240: 25.95		ROCK2_HUMAN (7-1344): 0: 714: 64.97
+	Hs
		527515 LAMP2_HUMAN (1-410): 0: 557: 100.00		MRCKA_HUMAN (668-1327): 3.6e-64: 242: 12.45
+	Hs
		507057 LAMP1_HUMAN (26-410): 3.76e-155: 446: 34.43		MRCKA_HUMAN (668-1327): 3.6e-64: 242: 12.45