HitPredict

Interactor 1: LAMP2 (P13473)
Lysosome-associated membrane glycoprotein 2 (LAMP-2) (Lysosome-associated membrane protein 2) (CD107 antigen-like family member B) (LGP-96) (CD antigen CD107b)
Gene: LAMP2

Interactor 2: SNX6 (Q9UNH7)
Sorting nexin-6 (TRAF4-associated factor 2) [Cleaved into: Sorting nexin-6, N-terminally processed]
Gene: SNX6

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	34079125
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005764 - lysosome
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 410 Hs			1 406
+	Hs
		527912 LAMP2_HUMAN (1-410): 0: 557: 100.00		SNX5_HUMAN (13-405): 3.75e-112: 336: 64.38
+	Hs
		240344 LAMP2_HUMAN (1-410): 0: 557: 100.00		SNX2_HUMAN (16-404): 1.6e-93: 292: 21.31
+	Hs
		527445 LAMP2_HUMAN (1-410): 0: 557: 100.00		SNX1_HUMAN (32-404): 3.57e-86: 273: 20.96
+	Hs
		507313 LAMP1_HUMAN (26-410): 3.76e-155: 446: 34.43		SNX6_HUMAN (1-406): 6.83e-126: 371: 100.00
+	Hs
		507336 LAMP1_HUMAN (26-410): 3.76e-155: 446: 34.43		SNX5_HUMAN (13-405): 3.75e-112: 336: 64.38
+	Hs
		507006 LAMP1_HUMAN (26-410): 3.76e-155: 446: 34.43		SNX1_HUMAN (32-404): 3.57e-86: 273: 20.96
+	Hs
		527885 LAMP2_HUMAN (1-410): 0: 557: 100.00		SNX12_HUMAN (32-170): 1.04e-14: 73.3: 20.98
+	Hs
		234896 LAMP2_HUMAN (1-410): 0: 557: 100.00		SNX3_HUMAN (32-170): 3.07e-14: 71.7: 20.28
+	Hs
		1357511 LAMP3_HUMAN (155-410): 7.26e-75: 240: 25.95		SNX6_HUMAN (1-406): 6.83e-126: 371: 100.00
+	Hs
		1357943 LAMP3_HUMAN (155-410): 7.26e-75: 240: 25.95		SNX5_HUMAN (13-405): 3.75e-112: 336: 64.38
+	Hs
		240459 LAMP3_HUMAN (155-410): 7.26e-75: 240: 25.95		SNX2_HUMAN (16-404): 1.6e-93: 292: 21.31
+	Hs
		234893 LAMP1_HUMAN (26-410): 3.76e-155: 446: 34.43		SNX3_HUMAN (32-170): 3.07e-14: 71.7: 20.28
+	Hs
		1040535 LAMP3_HUMAN (155-410): 7.26e-75: 240: 25.95		SNX1_HUMAN (32-404): 3.57e-86: 273: 20.96
+	Hs
		1357367 LAMP3_HUMAN (155-410): 7.26e-75: 240: 25.95		SNX12_HUMAN (32-170): 1.04e-14: 73.3: 20.98
+	Hs
		235010 LAMP3_HUMAN (155-410): 7.26e-75: 240: 25.95		SNX3_HUMAN (32-170): 3.07e-14: 71.7: 20.28