Interactor 1: CY24A (P13498)
Cytochrome b-245 light chain (Cytochrome b(558) alpha chain) (Cytochrome b558 subunit alpha) (Neutrophil cytochrome b 22 kDa polypeptide) (Superoxide-generating NADPH oxidase light chain subunit) (p22 phagocyte B-cytochrome) (p22-phox) (p22phox)
Gene: CYBA

Interactor 2: NCF1 (P14598)
Neutrophil cytosol factor 1 (NCF-1) (47 kDa autosomal chronic granulomatous disease protein) (47 kDa neutrophil oxidase factor) (NCF-47K) (Neutrophil NADPH oxidase factor 1) (Nox organizer 2) (Nox-organizing protein 2) (SH3 and PX domain-containing protein 1A) (p47-phox)
Gene: NCF1

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.86 0.60 0.720

The method score is based on:

Property Details
Experiments 7938008, 36163178, 12056906, 17803994, 16326715
Identification Methods pull down, affinity chromatography technology, far western blotting, nuclear magnetic resonance, classical fluorescence spectroscopy, biophysical
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005886 - plasma membrane
GO:0006801 - superoxide metabolic process
GO:0009055 - electron transfer activity
GO:0016020 - membrane
GO:0017124 - SH3 domain binding
and 4 others

more...

Homologous interactions 3

Homologous interactions

Color coding for hit scores

1 195
Hs

1 390
+ Hs
+ Mm
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024