HitPredict

Interactor 1: CCL2 (P13500)
C-C motif chemokine 2 (HC11) (Monocyte chemoattractant protein 1) (Monocyte chemotactic and activating factor) (MCAF) (Monocyte chemotactic protein 1) (MCP-1) (Monocyte secretory protein JE) (Small-inducible cytokine A2)
Gene: CCL2

Interactor 2: CCL11 (P51671)
Eotaxin (C-C motif chemokine 11) (Eosinophil chemotactic protein) (Small-inducible cytokine A11)
Gene: CCL11

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.62 1.00 0.789

The method score is based on:

Property Details
Experiments 28381538, 16803905
Identification Methods pull down, mass spectrometry studies of complexes, filter binding
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains IL8~IL8
Common GO terms GO:0002548 - monocyte chemotaxis
GO:0005576 - extracellular region
GO:0005615 - extracellular space
GO:0006468 - protein phosphorylation
GO:0007155 - cell adhesion
and 16 others

more...
Homologous interactions 18

Homologous interactions

Color coding for hit scores

1 99
Hs

1 97
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024