Interactor 1: CCL5 (P13501)
C-C motif chemokine 5 (EoCP) (Eosinophil chemotactic cytokine) (SIS-delta) (Small-inducible cytokine A5) (T cell-specific protein P228) (TCP228) (T-cell-specific protein RANTES) [Cleaved into: RANTES(3-68); RANTES(4-68)]
Gene: CCL5

Interactor 2: CCL5 (P13501)
C-C motif chemokine 5 (EoCP) (Eosinophil chemotactic cytokine) (SIS-delta) (Small-inducible cytokine A5) (T cell-specific protein P228) (TCP228) (T-cell-specific protein RANTES) [Cleaved into: RANTES(3-68); RANTES(4-68)]
Gene: CCL5

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.82 1.00 0.906

The method score is based on:

Property Details
Experiments 15530372, 21827949, 28381538, 23480650
Identification Methods x-ray crystallography, dynamic light scattering, nuclear magnetic resonance, x ray scattering, mass spectrometry studies of complexes, surface plasmon resonance
Interaction Type direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains IL8~IL8
Common GO terms GO:0002407 - dendritic cell chemotaxis
GO:0002548 - monocyte chemotaxis
GO:0002676 - regulation of chronic inflammatory response
GO:0004435 - phosphatidylinositol phospholipase C activity
GO:0004672 - protein kinase activity
and 69 others

more...

Homologous interactions 18

Homologous interactions

Color coding for hit scores

1 91
Hs

1 91
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Last updated: 15 Jul 2024