HitPredict

Interactor 1: CCL5 (P13501)
C-C motif chemokine 5 (EoCP) (Eosinophil chemotactic cytokine) (SIS-delta) (Small-inducible cytokine A5) (T cell-specific protein P228) (TCP228) (T-cell-specific protein RANTES) [Cleaved into: RANTES(3-68); RANTES(4-68)]
Gene: CCL5

Interactor 2: CXCR5 (P32302)
C-X-C chemokine receptor type 5 (CXC-R5) (CXCR-5) (Burkitt lymphoma receptor 1) (Monocyte-derived receptor 15) (MDR-15) (CD antigen CD185)
Gene: CXCR5

Species: Homo sapiens

Source: dip

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	9312096
Identification Methods	biochemical
Interaction Type	physical association

Property	Details
Interacting Pfam domains	7tm_1~IL8
Common GO terms	GO:0007186 - G protein-coupled receptor signaling pathway
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 91 Hs			1 372
+	Hs
		486231 CCL3_HUMAN (1-91): 3.36e-37: 121: 49.45		CXCR5_HUMAN (1-372): 1.08e-91: 281: 100.00
+	Hs
		526561 CCL4_HUMAN (1-91): 1.04e-35: 118: 45.65		CXCR5_HUMAN (1-372): 1.08e-91: 281: 100.00
+	Hs
		486237 CCL3_HUMAN (1-91): 3.36e-37: 121: 49.45		CCR3_HUMAN (21-367): 2.57e-74: 236: 28.45
+	Hs
		561732 CL3L1_HUMAN (1-91): 2.63e-37: 121: 46.74		CCR3_HUMAN (21-367): 2.57e-74: 236: 28.45
+	Hs
		830629 CCL13_HUMAN (1-90): 5.7e-36: 118: 31.87		CXCR3_HUMAN (14-350): 4.44e-75: 238: 39.76
+	Hs
		526564 CCL4_HUMAN (1-91): 1.04e-35: 118: 45.65		CCR3_HUMAN (21-367): 2.57e-74: 236: 28.45
+	Hs
		849619 CCL13_HUMAN (1-90): 5.7e-36: 118: 31.87		CCR3_HUMAN (21-367): 2.57e-74: 236: 28.45
+	Hs
		783833 CCL13_HUMAN (1-90): 5.7e-36: 118: 31.87		CCR2_HUMAN (30-349): 1.29e-72: 232: 29.69
+	Hs
		486230 CCL3_HUMAN (1-91): 3.36e-37: 121: 49.45		CCR1_HUMAN (33-367): 2.52e-71: 228: 27.68
+	Hs
		561728 CL3L1_HUMAN (1-91): 2.63e-37: 121: 46.74		CCR1_HUMAN (33-367): 2.52e-71: 228: 27.68
+	Hs
		526560 CCL4_HUMAN (1-91): 1.04e-35: 118: 45.65		CCR1_HUMAN (33-367): 2.52e-71: 228: 27.68
+	Hs
		486238 CCL3_HUMAN (1-91): 3.36e-37: 121: 49.45		CCR4_HUMAN (9-369): 2.41e-67: 218: 29.83
+	Hs
		486239 CCL3_HUMAN (1-91): 3.36e-37: 121: 49.45		CCR5_HUMAN (23-368): 2.9e-66: 215: 26.59
+	Hs
		561733 CL3L1_HUMAN (1-91): 2.63e-37: 121: 46.74		CCR5_HUMAN (23-368): 2.9e-66: 215: 26.59
+	Hs
		526565 CCL4_HUMAN (1-91): 1.04e-35: 118: 45.65		CCR5_HUMAN (23-368): 2.9e-66: 215: 26.59
+	Hs
		849654 CCL13_HUMAN (1-90): 5.7e-36: 118: 31.87		CCR5_HUMAN (23-368): 2.9e-66: 215: 26.59
+	Hs
		1305163 CCL13_HUMAN (1-90): 5.7e-36: 118: 31.87		ACKR4_HUMAN (7-349): 3.48e-65: 212: 27.99
+	Hs
		134354 CCL3_HUMAN (1-91): 3.36e-37: 121: 49.45		ACKR2_HUMAN (46-340): 4.16e-36: 137: 32.23
+	Hs
		134356 CCL4_HUMAN (1-91): 1.04e-35: 118: 45.65		ACKR2_HUMAN (46-340): 4.16e-36: 137: 32.23
+	Hs
		134400 CCL13_HUMAN (1-90): 5.7e-36: 118: 31.87		ACKR2_HUMAN (46-340): 4.16e-36: 137: 32.23