HitPredict

Interactor 1: CCL5 (P13501)
C-C motif chemokine 5 (EoCP) (Eosinophil chemotactic cytokine) (SIS-delta) (Small-inducible cytokine A5) (T cell-specific protein P228) (TCP228) (T-cell-specific protein RANTES) [Cleaved into: RANTES(3-68); RANTES(4-68)]
Gene: CCL5

Interactor 2: CCL28 (Q9NRJ3)
C-C motif chemokine 28 (Mucosae-associated epithelial chemokine) (MEC) (Protein CCK1) (Small-inducible cytokine A28)
Gene: CCL28

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.51	1.00	0.716

Property	Details
Experiments	28381538
Identification Methods	pull down, surface plasmon resonance, filter binding
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	IL8~IL8
Common GO terms	GO:0005576 - extracellular region GO:0006935 - chemotaxis GO:0008009 - chemokine activity
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 91 Hs			1 127
+	Hs
		1305164 CCL13_HUMAN (1-90): 5.7e-36: 118: 31.87		CCL28_HUMAN (1-127): 1.92e-68: 203: 100.00
+	Hs
		849514 CCL11_HUMAN (1-90): 8.16e-28: 98.1: 41.76		CCL28_HUMAN (1-127): 1.92e-68: 203: 100.00
+	Hs
		1344885 CCL26_HUMAN (21-89): 8.09e-25: 90.8: 40.58		CCL28_HUMAN (1-127): 1.92e-68: 203: 100.00
+	Hs
		1267674 CCL17_HUMAN (1-89): 3.41e-23: 86.5: 28.09		CCL28_HUMAN (1-127): 1.92e-68: 203: 100.00
+	Hs
		815520 XCL1_HUMAN (1-90): 3.92e-22: 84.2: 33.33		CCL28_HUMAN (1-127): 1.92e-68: 203: 100.00
+	Hs
		1344883 XCL2_HUMAN (1-90): 7.46e-22: 83.8: 33.33		CCL28_HUMAN (1-127): 1.92e-68: 203: 100.00
+	Hs
		134313 CCL21_HUMAN (23-91): 1.24e-18: 76.1: 28.77		CCL28_HUMAN (1-127): 1.92e-68: 203: 100.00
+	Hs
		528282 CCL5_HUMAN (1-91): 4.43e-31: 106: 100.00		CCL27_HUMAN (23-94): 1.8e-37: 124: 39.73
+	Hs
		849516 CCL11_HUMAN (1-90): 8.16e-28: 98.1: 41.76		CCL27_HUMAN (23-94): 1.8e-37: 124: 39.73