HitPredict

Interactor 1: CFTR (P13569)
Cystic fibrosis transmembrane conductance regulator (CFTR) (ATP-binding cassette sub-family C member 7) (Channel conductance-controlling ATPase) (EC 5.6.1.6) (cAMP-dependent chloride channel)
Gene: CFTR

Interactor 2: PSB1 (P20618)
Proteasome subunit beta type-1 (Macropain subunit C5) (Multicatalytic endopeptidase complex subunit C5) (Proteasome component C5) (Proteasome gamma chain)
Gene: PSMB1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.71	0.60	0.656

Property	Details
Experiments	26618866, 31324722, 17110338
Identification Methods	affinity chromatography technology, anti bait coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 1480 Hs			1 241
+	Hs
		528772 CFTR_HUMAN (1-1480): 0: 1031: 100.00		PSB3_HUMAN (31-241): 3.45e-82: 246: 23.94
+	Hs
		156210 CFTR_HUMAN (1-1480): 0: 1031: 100.00		PSA7_HUMAN (17-241): 8.16e-79: 238: 13.54
+	Hs
		528597 CFTR_HUMAN (1-1480): 0: 1031: 100.00		PSB8_HUMAN (14-230): 1.02e-77: 237: 21.27
+	Hs
		528866 CFTR_HUMAN (1-1480): 0: 1031: 100.00		PSA6_HUMAN (17-240): 4.32e-77: 234: 14.91
+	Hs
		528582 CFTR_HUMAN (1-1480): 0: 1031: 100.00		PSA4_HUMAN (8-240): 1.49e-75: 231: 17.72
+	Hs
		528598 CFTR_HUMAN (1-1480): 0: 1031: 100.00		PSA5_HUMAN (16-240): 7.6e-75: 228: 16.67
+	Hs
		528601 CFTR_HUMAN (1-1480): 0: 1031: 100.00		PSB5_HUMAN (9-230): 4.76e-73: 224: 20.27
+	Hs
		528600 CFTR_HUMAN (1-1480): 0: 1031: 100.00		PSB6_HUMAN (34-236): 8.15e-56: 180: 21.68
+	Hs
		528773 CFTR_HUMAN (1-1480): 0: 1031: 100.00		PSB2_HUMAN (40-233): 2.78e-09: 57: 24.62
+	Zm
		74636 K7W6A4_MAIZE (8-648): 1.11e-59: 228: 15.10		B4FDY6_MAIZE (8-226): 2.22e-77: 235: 16.59