HitPredict

Interactor 1: CFTR (P13569)
Cystic fibrosis transmembrane conductance regulator (CFTR) (ATP-binding cassette sub-family C member 7) (Channel conductance-controlling ATPase) (EC 5.6.1.6) (cAMP-dependent chloride channel)
Gene: CFTR

Interactor 2: 2AAA (P30153)
Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform (Medium tumor antigen-associated 61 kDa protein) (PP2A subunit A isoform PR65-alpha) (PP2A subunit A isoform R1-alpha)
Gene: PPP2R1A

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.87	0.60	0.724

Property	Details
Experiments	26618866, 31324722, 17110338, 15936019, 29924966
Identification Methods	affinity chromatography technology, anti bait coimmunoprecipitation, pull down, cross-linking study, two hybrid array
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0016020 - membrane
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 1480 Hs			1 589
+	Hs
		528622 CFTR_HUMAN (1-1480): 0: 1031: 100.00		2AAB_HUMAN (9-589): 7.23e-158: 466: 86.40
+	Hs
		268592 CFTR_HUMAN (1-1480): 0: 1031: 100.00		SF3B1_HUMAN (12-589): 2.5e-28: 122: 13.20
+	Hs
		529496 CFTR_HUMAN (1-1480): 0: 1031: 100.00		GCN1_HUMAN (28-589): 5.37e-25: 112: 16.01
+	Hs
		529511 CFTR_HUMAN (1-1480): 0: 1031: 100.00		TNPO1_HUMAN (24-483): 2.91e-20: 97.2: 15.05
+	Dm
		734193 Q7KTD0_DROME (788-1466): 6.87e-53: 206: 14.95		2AAA_DROME (1-578): 2.84e-146: 436: 75.35