HitPredict

Interactor 1: CFTR (P13569)
Cystic fibrosis transmembrane conductance regulator (CFTR) (ATP-binding cassette sub-family C member 7) (Channel conductance-controlling ATPase) (EC 5.6.1.6) (cAMP-dependent chloride channel)
Gene: CFTR

Interactor 2: HNRH2 (P55795)
Heterogeneous nuclear ribonucleoprotein H2 (hnRNP H2) (FTP-3) (Heterogeneous nuclear ribonucleoprotein H') (hnRNP H') [Cleaved into: Heterogeneous nuclear ribonucleoprotein H2, N-terminally processed]
Gene: HNRNPH2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	31324722
Identification Methods	affinity chromatography technology, cross-linking study
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005829 - cytosol GO:0016020 - membrane
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 1480 Hs			1 449
+	Hs
		529069 CFTR_HUMAN (1-1480): 0: 1031: 100.00		PABP4_HUMAN (1-447): 1.01e-81: 266: 13.59
+	Hs
		516343 CFTR_HUMAN (1-1480): 0: 1031: 100.00		PABP1_HUMAN (1-448): 4.82e-81: 264: 12.29
+	Hs
		529709 CFTR_HUMAN (1-1480): 0: 1031: 100.00		PABP3_HUMAN (1-446): 2.6e-77: 254: 12.23
+	Hs
		529208 CFTR_HUMAN (1-1480): 0: 1031: 100.00		PAP1L_HUMAN (1-446): 4e-77: 253: 12.42
+	Hs
		528638 CFTR_HUMAN (1-1480): 0: 1031: 100.00		HNRH1_HUMAN (1-449): 2.8e-73: 239: 96.21
+	Hs
		528812 CFTR_HUMAN (1-1480): 0: 1031: 100.00		HNRPF_HUMAN (1-434): 2.49e-60: 204: 71.72
+	Hs
		528637 CFTR_HUMAN (1-1480): 0: 1031: 100.00		HNRH3_HUMAN (10-86): 8.49e-10: 62.2: 33.77
+	Hs
		528516 CFTR_HUMAN (1-1480): 0: 1031: 100.00		NUCL_HUMAN (4-404): 6.61e-09: 60.2: 18.16
+	Sc
		376791 YCFI_YEAST (748-1433): 4.8e-56: 216: 14.59		PABP_YEAST (103-370): 5.77e-34: 135: 13.87
+	Hs
		582437 MRP9_HUMAN (129-648): 1.25e-56: 218: 14.61		NUCL_HUMAN (4-404): 6.61e-09: 60.2: 18.16