Protein: RLA3
Large ribosomal subunit protein P1B (P1B) (60S acidic ribosomal protein P1-beta) (Ax) (L12eIIB) (L44') (YP1beta)

Gene: RLA3, RPP1B
Organism: Saccharomyces cerevisiae S288C
Interactions: 140
UniProt ID: P10622

Gene Ontology (top 5):
GO:0000324 - fungal-type vacuole
GO:0002181 - cytoplasmic translation
GO:0003735 - structural constituent of ribosome
GO:0006414 - translational elongation
GO:0022625 - cytosolic large ribosomal subunit

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

427101

RLA0
Large ribosomal subunit protein uL10

4

7

Small-scale

0.904

High

383068

RLA4
Large ribosomal subunit protein P2B

5

8

Small-scale

0.901

High

427653

RLA2
Large ribosomal subunit protein P2A

4

8

Small-scale

0.881

High

427531

RLA1
Large ribosomal subunit protein P1A

3

4

Small-scale

0.829

High

528786

RLA3
Large ribosomal subunit protein P1B

1

4

Small-scale

0.618

High

528800

RL16A
Large ribosomal subunit protein uL13A

2

3

High-throughput

0.584

High

528879

TMA46
Translation machinery-associated protein 46

2

1

High-throughput

0.584

High

528852

BRE5
UBP3-associated protein BRE5

2

2

High-throughput

0.558

High

481956

C1TM
C-1-tetrahydrofolate synthase, mitochondrial

2

1

High-throughput

0.549

High

528808

SPT7
SAGA complex subunit SPT7

1

4

High-throughput

0.489

High

528814

TAF5
SAGA complex/transcription factor TFIID complex subunit TAF5

1

3

High-throughput

0.489

High

528846

TAF6
SAGA complex/transcription factor TFIID complex subunit TAF6

1

1

High-throughput

0.489

High

528858

UBP3
Ubiquitin carboxyl-terminal hydrolase 3

1

2

High-throughput

0.489

High

528863

GCN5
Histone acetyltransferase GCN5

1

1

High-throughput

0.489

High

528864

TAF12
SAGA complex/transcription factor TFIID complex subunit TAF12

1

1

High-throughput

0.489

High

528888

SUS1
SAGA complex subunit SUS1

1

2

High-throughput

0.489

High

154125

RL36B
Large ribosomal subunit protein eL36B

1

3

High-throughput

0.479

High

409679

RL24A
Large ribosomal subunit protein eL24A

1

1

High-throughput

0.479

High

409881

RL25
Large ribosomal subunit protein uL23

1

1

High-throughput

0.479

High

432463

RL7A
Large ribosomal subunit protein uL30A

1

4

High-throughput

0.479

High

432787

RL9A
Large ribosomal subunit protein uL6A

1

1

High-throughput

0.479

High

432964

RL6B
Large ribosomal subunit protein eL6B

1

3

High-throughput

0.479

High

433131

RL17A
Large ribosomal subunit protein uL22A

1

3

High-throughput

0.479

High

433389

RL26A
Large ribosomal subunit protein uL24A

1

2

High-throughput

0.479

High

433958

RL33A
Large ribosomal subunit protein eL33A

1

2

High-throughput

0.479

High

434227

RL29
Large ribosomal subunit protein eL29

1

1

High-throughput

0.479

High

434309

RL15A
Large ribosomal subunit protein eL15A

1

1

High-throughput

0.479

High

434504

RL22A
Large ribosomal subunit protein eL22A

1

2

High-throughput

0.479

High

503347

RL11A
Large ribosomal subunit protein uL5A

1

3

High-throughput

0.479

High

503740

RL27A
Large ribosomal subunit protein eL27A

1

2

High-throughput

0.479

High

503887

RL27B
Large ribosomal subunit protein eL27B

1

2

High-throughput

0.479

High

511122

RL20B
Large ribosomal subunit protein eL20B

1

1

High-throughput

0.479

High

511362

RL43B
Large ribosomal subunit protein eL43B

1

1

High-throughput

0.479

High

513446

RL1A
Large ribosomal subunit protein uL1A

1

1

High-throughput

0.479

High

513615

RL2A
Large ribosomal subunit protein uL2A

1

1

High-throughput

0.479

High

513939

RL18B
Large ribosomal subunit protein eL18B

1

1

High-throughput

0.479

High

514220

RL12B
Large ribosomal subunit protein uL11B

1

1

High-throughput

0.479

High

515030

RL19B
Large ribosomal subunit protein eL19

1

2

High-throughput

0.479

High

515198

RL35A
Large ribosomal subunit protein uL29A

1

1

High-throughput

0.479

High

528787

RL4A
Large ribosomal subunit protein uL4A

1

3

High-throughput

0.479

High

528789

RL30
Large ribosomal subunit protein eL30

1

1

High-throughput

0.479

High

528790

RL3
Large ribosomal subunit protein uL3

1

2

High-throughput

0.479

High

528791

RL8A
Large ribosomal subunit protein eL8A

1

4

High-throughput

0.479

High

528793

RL24B
Large ribosomal subunit protein eL24B

1

1

High-throughput

0.479

High

528798

RL5
Large ribosomal subunit protein uL18

1

2

High-throughput

0.479

High

528801

RL16B
Large ribosomal subunit protein uL13B

1

3

High-throughput

0.479

High

528804

RL8B
Large ribosomal subunit protein eL8B

1

4

High-throughput

0.479

High

528809

RL14A
Large ribosomal subunit protein eL14A

1

4

High-throughput

0.479

High

528813

RL32
Large ribosomal subunit protein eL32

1

1

High-throughput

0.479

High

528816

RL14B
Large ribosomal subunit protein eL14B

1

4

High-throughput

0.479

High

528819

STM1
Suppressor protein STM1

1

1

High-throughput

0.479

High

528823

RBG1
Ribosome-interacting GTPase 1

1

2

High-throughput

0.479

High

528828

RL13B
Large ribosomal subunit protein eL13B

1

3

High-throughput

0.479

High

528830

RL34B
Large ribosomal subunit protein eL34B

1

3

High-throughput

0.479

High

528832

RLP7
Ribosome biogenesis protein RLP7

1

4

High-throughput

0.479

High

528833

RL33B
Large ribosomal subunit protein eL33B

1

2

High-throughput

0.479

High

528834

RL10
Large ribosomal subunit protein uL16

1

1

High-throughput

0.479

High

528836

RL17B
Large ribosomal subunit protein uL22B

1

3

High-throughput

0.479

High

528841

RL37A
Large ribosomal subunit protein eL37A

1

1

High-throughput

0.479

High

528842

RL38
Large ribosomal subunit protein eL38

1

1

High-throughput

0.479

High

528845

RL37B
Large ribosomal subunit protein eL37B

1

1

High-throughput

0.479

High

528848

RL26B
Large ribosomal subunit protein uL24B

1

2

High-throughput

0.479

High

528856

RL22B
Large ribosomal subunit protein eL22B

1

2

High-throughput

0.479

High

528857

RL34A
Large ribosomal subunit protein eL34A

1

3

High-throughput

0.479

High

528859

RL6A
Large ribosomal subunit protein eL6A

1

3

High-throughput

0.479

High

528860

RL21A
Large ribosomal subunit protein eL21A

1

3

High-throughput

0.479

High

528885

RL21B
Large ribosomal subunit protein eL21B

1

3

High-throughput

0.479

High

528887

RL11B
Large ribosomal subunit protein uL5B

1

3

High-throughput

0.479

High

383252

RL28
Large ribosomal subunit protein uL15

1

0

High-throughput

0.458

High

503986

RL31A
Large ribosomal subunit protein eL31A

1

0

High-throughput

0.458

High

511535

RL44B
Large ribosomal subunit protein eL42B

1

0

High-throughput

0.458

High

515357

RS32B
Small ribosomal subunit protein eS32B

1

0

High-throughput

0.458

High

528820

YCFI
Metal resistance protein YCF1

1

0

High-throughput

0.458

High

528805

EF2
Elongation factor 2

1

2

Small-scale

0.457

High

392097

HSP82
ATP-dependent molecular chaperone HSP82

1

2

High-throughput

0.437

High

438593

SC160
Protein SCP160

1

2

High-throughput

0.437

High

528788

ACOX
Acyl-coenzyme A oxidase

1

1

High-throughput

0.437

High

528794

DBP2
ATP-dependent RNA helicase DBP2

1

1

High-throughput

0.437

High

528796

KRR1
KRR1 small subunit processome component

1

1

High-throughput

0.437

High

528797

SPB4
ATP-dependent rRNA helicase SPB4

1

4

High-throughput

0.437

High

528802

TF2B
Transcription initiation factor IIB

1

3

High-throughput

0.437

High

528803

TF3B
Transcription factor IIIB 70 kDa subunit

1

3

High-throughput

0.437

High

528811

GLYM
Serine hydroxymethyltransferase, mitochondrial

1

1

High-throughput

0.437

High

528822

LAA1
AP-1 accessory protein LAA1

1

1

High-throughput

0.437

High

528824

IF2P
Eukaryotic translation initiation factor 5B

1

1

High-throughput

0.437

High

528825

NOC2
Nucleolar complex protein 2

1

1

Small-scale

0.437

High

528826

IF4F2
Eukaryotic initiation factor 4F subunit p130

1

1

High-throughput

0.437

High

528831

DSN1
Kinetochore-associated protein DSN1

1

1

High-throughput

0.437

High

528835

UTP10
U3 small nucleolar RNA-associated protein 10

1

1

High-throughput

0.437

High

528838

MOG1
Nuclear import protein MOG1

1

1

High-throughput

0.437

High

528850

H1
Histone H1

1

1

High-throughput

0.437

High

528853

GIS2
Zinc finger protein GIS2

1

2

High-throughput

0.437

High

528854

JJJ1
J protein JJJ1

1

2

High-throughput

0.437

High

528855

APJ1
J domain-containing protein APJ1

1

1

High-throughput

0.437

High

528862

TOM1
E3 ubiquitin-protein ligase TOM1

1

2

High-throughput

0.437

High

528865

HMO1
High mobility group protein 1

1

1

High-throughput

0.437

High

528870

VMS1
tRNA endonuclease VMS1

1

1

High-throughput

0.437

High

528871

LTN1
E3 ubiquitin-protein ligase listerin

1

1

Small-scale

0.437

High

528873

RQC1
Ribosome quality control complex subunit 1

1

1

Small-scale

0.437

High

528877

ELP1
Elongator complex protein 1

1

1

High-throughput

0.437

High

528881

YRA1
RNA annealing protein YRA1

1

1

High-throughput

0.437

High

528883

RUVB2
RuvB-like protein 2

1

2

High-throughput

0.437

High

528884

RQC2
Ribosome quality control complex subunit 2

1

1

High-throughput

0.437

High

528827

SSB2
Ribosome-associated molecular chaperone SSB2

1

0

High-throughput

0.426

High

528818

SPT8
SAGA complex subunit SPT8

1

1

High-throughput

0.407

High

528843

UBP8
Ubiquitin carboxyl-terminal hydrolase 8

1

2

High-throughput

0.407

High

528844

SPT20
SAGA complex subunit SPT20

1

1

High-throughput

0.407

High

528872

TAF9
SAGA complex/transcription factor TFIID complex subunit TAF9

1

1

High-throughput

0.407

High

528874

YL287
Uncharacterized protein YLR287C

1

0

High-throughput

0.282

High

528795

SGF29
SAGA complex subunit SGF29

1

0

High-throughput

0.279

Low

528847

SGF73
SAGA complex subunit SGF73

1

0

High-throughput

0.279

Low

528812

PAM1
Protein PAM1

1

0

High-throughput

0.269

Low

528861

RLI1
Translation initiation factor RLI1

1

0

High-throughput

0.269

Low

517852

SSBP1
Single-stranded nucleic acid-binding protein

1

0

High-throughput

0.261

Low

528792

RAD53
Serine/threonine-protein kinase RAD53

1

0

High-throughput

0.249

Low

528815

GID4
GID complex substrate-recognition subunit 4

1

0

High-throughput

0.249

Low

528817

CRP1
Cruciform DNA-recognizing protein 1 [Cleaved into: CRP1 short N-terminal subpeptide; CRP1 short C-terminal subpeptide]

1

0

High-throughput

0.249

Low

528821

ATC3
Phospholipid-transporting ATPase DRS2

1

0

High-throughput

0.249

Low

528829

TM108
Protein TMA108

1

0

High-throughput

0.249

Low

528840

VATG
V-type proton ATPase subunit G

1

0

High-throughput

0.249

Low

528849

EIF2A
Eukaryotic translation initiation factor 2A

1

0

High-throughput

0.249

Low

528851

COPA
Coatomer subunit alpha

1

0

High-throughput

0.249

Low

528866

RRP17
Ribosomal RNA-processing protein 17

1

0

High-throughput

0.249

Low

528868

DHR1
Probable ATP-dependent RNA helicase DHR1

1

0

High-throughput

0.249

Low

528869

PDS5
Sister chromatid cohesion protein PDS5

1

0

High-throughput

0.249

Low

528875

MMS22
E3 ubiquitin-protein ligase substrate receptor MMS22

1

0

High-throughput

0.249

Low

528878

AP3D
AP-3 complex subunit delta

1

0

High-throughput

0.249

Low

528886

SMC6
Structural maintenance of chromosomes protein 6

1

0

High-throughput

0.249

Low

470195

NUC1
Mitochondrial nuclease

1

0

High-throughput

0.238

Low

528799

RFA3
Replication factor A protein 3

1

0

High-throughput

0.238

Low

528806

MG101
Mitochondrial genome maintenance protein MGM101

1

0

High-throughput

0.238

Low

528807

PEX2
Peroxisomal biogenesis factor 2

1

0

High-throughput

0.238

Low

528810

DID4
DOA4-independent degradation protein 4

1

0

High-throughput

0.238

Low

528837

YJY2
Uncharacterized protein YJR012C

1

0

High-throughput

0.238

Low

528839

ABM1
Aberrant microtubules protein 1

1

0

High-throughput

0.238

Low

528867

HPRT
Hypoxanthine-guanine phosphoribosyltransferase

1

0

High-throughput

0.238

Low

528876

KEI1
Inositol phosphorylceramide synthase regulatory subunit KEI1

1

0

High-throughput

0.238

Low

528880

FCF2
rRNA-processing protein FCF2

1

0

High-throughput

0.238

Low

528882

RAD59
DNA repair protein RAD59

1

0

High-throughput

0.238

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025