HitPredict

Interactor 1: CFTR (P13569)
Cystic fibrosis transmembrane conductance regulator (CFTR) (ATP-binding cassette sub-family C member 7) (Channel conductance-controlling ATPase) (EC 5.6.1.6) (cAMP-dependent chloride channel)
Gene: CFTR

Interactor 2: LAMB3 (Q13751)
Laminin subunit beta-3 (Epiligrin subunit bata) (Kalinin B1 chain) (Kalinin subunit beta) (Laminin B1k chain) (Laminin-5 subunit beta) (Nicein subunit beta)
Gene: LAMB3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.50	0.574

Property	Details
Experiments	26618866, 31324722
Identification Methods	affinity chromatography technology, cross-linking study, anti bait coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 1480 Hs			1 1172
+	Hs
		172639 CFTR_HUMAN (1-1480): 0: 1031: 100.00		LAMA5_HUMAN (152-326): 1.32e-12: 74.9: 15.51
+	Hs
		529190 CFTR_HUMAN (1-1480): 0: 1031: 100.00		LAMA3_HUMAN (528-684): 3.24e-10: 67.2: 11.95
+	Dm
		422883 Q9VK56_DROME (788-1466): 8.66e-53: 206: 14.95		NOTCH_DROME (331-677): 4.15e-33: 141: 15.93
+	Dm
		1098814 Q9VLN6_DROME (917-1477): 1.23e-61: 234: 17.69		NETB_DROME (451-571): 5.21e-09: 62.8: 27.27
+	Dm
		1098777 Q9VJ21_DROME (835-1477): 3.83e-60: 229: 16.67		NETB_DROME (451-571): 5.21e-09: 62.8: 27.27
+	Dm
		954673 L259_DROME (42-639): 1.85e-59: 227: 15.27		NETB_DROME (451-571): 5.21e-09: 62.8: 27.27
+	Dm
		1098553 Q8MT77_DROME (80-635): 6.53e-58: 222: 13.33		NETB_DROME (451-571): 5.21e-09: 62.8: 27.27
+	Dm
		1099070 Q9W2I5_DROME (51-671): 1.32e-52: 205: 14.15		NETB_DROME (451-571): 5.21e-09: 62.8: 27.27
+	Dm
		1098580 Q961D3_DROME (798-1478): 2.6e-52: 204: 15.42		NETB_DROME (451-571): 5.21e-09: 62.8: 27.27