HitPredict

Interactor 1: CFTR (P13569)
Cystic fibrosis transmembrane conductance regulator (CFTR) (ATP-binding cassette sub-family C member 7) (Channel conductance-controlling ATPase) (EC 5.6.1.6) (cAMP-dependent chloride channel)
Gene: CFTR

Interactor 2: LAMC2 (Q13753)
Laminin subunit gamma-2 (Cell-scattering factor 140 kDa subunit) (CSF 140 kDa subunit) (Epiligrin subunit gamma) (Kalinin subunit gamma) (Kalinin/nicein/epiligrin 100 kDa subunit) (Ladsin 140 kDa subunit) (Laminin B2t chain) (Laminin-5 subunit gamma) (Large adhesive scatter factor 140 kDa subunit) (Nicein subunit gamma)
Gene: LAMC2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.50	0.489

Property	Details
Experiments	31324722
Identification Methods	affinity chromatography technology, cross-linking study
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 1480 Hs			1 1193
+	Hs
		529086 CFTR_HUMAN (1-1480): 0: 1031: 100.00		LAMB3_HUMAN (8-188): 2.19e-30: 132: 31.94
+	Hs
		522533 CFTR_HUMAN (1-1480): 0: 1031: 100.00		MYH1_HUMAN (640-1106): 5.8e-28: 125: 10.37
+	Hs
		528400 CFTR_HUMAN (1-1480): 0: 1031: 100.00		MYH8_HUMAN (617-1019): 1.13e-15: 85: 15.90
+	Hs
		529895 CFTR_HUMAN (1-1480): 0: 1031: 100.00		MYH2_HUMAN (617-1013): 9.72e-15: 81.9: 16.20
+	Hs
		172639 CFTR_HUMAN (1-1480): 0: 1031: 100.00		LAMA5_HUMAN (167-420): 4.63e-12: 73.1: 11.49
+	Hs
		529190 CFTR_HUMAN (1-1480): 0: 1031: 100.00		LAMA3_HUMAN (166-370): 5.92e-09: 63.1: 11.01
+	Dm
		422883 Q9VK56_DROME (788-1466): 8.66e-53: 206: 14.95		NOTCH_DROME (304-732): 1.93e-28: 127: 14.44