HitPredict

Interactor 1: CFTR (P13569)
Cystic fibrosis transmembrane conductance regulator (CFTR) (ATP-binding cassette sub-family C member 7) (Channel conductance-controlling ATPase) (EC 5.6.1.6) (cAMP-dependent chloride channel)
Gene: CFTR

Interactor 2: TBB2A (Q13885)
Tubulin beta-2A chain (Tubulin beta class IIa)
Gene: TUBB2A

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	31324722
Identification Methods	affinity chromatography technology, cross-linking study
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 1480 Hs			1 445
+	Hs
		529079 CFTR_HUMAN (1-1480): 0: 1031: 100.00		TBB3_HUMAN (1-445): 0: 715: 91.93
+	Hs
		427992 CFTR_HUMAN (1-1480): 0: 1031: 100.00		TBB5_HUMAN (1-429): 0: 714: 96.97
+	Hs
		528958 CFTR_HUMAN (1-1480): 0: 1031: 100.00		TBB4B_HUMAN (1-427): 0: 713: 97.66
+	Hs
		529674 CFTR_HUMAN (1-1480): 0: 1031: 100.00		TBB2B_HUMAN (1-430): 0: 712: 99.54
+	Hs
		529665 CFTR_HUMAN (1-1480): 0: 1031: 100.00		TBB6_HUMAN (1-432): 0: 709: 92.13
+	Hs
		529204 CFTR_HUMAN (1-1480): 0: 1031: 100.00		TBB8_HUMAN (1-427): 0: 697: 89.93
+	Hs
		1037335 MRP2_HUMAN (798-1466): 4.31e-56: 217: 15.74		TBB3_HUMAN (1-445): 0: 715: 91.93