HitPredict

Interactor 1: CFTR (P13569)
Cystic fibrosis transmembrane conductance regulator (CFTR) (ATP-binding cassette sub-family C member 7) (Channel conductance-controlling ATPase) (EC 5.6.1.6) (cAMP-dependent chloride channel)
Gene: CFTR

Interactor 2: DJB14 (Q8TBM8)
DnaJ homolog subfamily B member 14
Gene: DNAJB14

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.61	0.60	0.608

Property	Details
Experiments	35156780, 26618866
Identification Methods	protein complementation assay, ubiquitin reconstruction, anti bait coimmunoprecipitation
Interaction Type	direct interaction, physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005789 - endoplasmic reticulum membrane GO:0016020 - membrane
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 1480 Hs			1 379
+	Hs
		529804 CFTR_HUMAN (1-1480): 0: 1031: 100.00		DJB12_HUMAN (1-378): 4.05e-127: 371: 50.79
+	Hs
		279273 CFTR_HUMAN (1-1480): 0: 1031: 100.00		DNJB5_HUMAN (106-253): 1.4e-48: 169: 35.81
+	Hs
		529547 CFTR_HUMAN (1-1480): 0: 1031: 100.00		DNJA3_HUMAN (60-251): 1.68e-43: 158: 24.87
+	Hs
		528576 CFTR_HUMAN (1-1480): 0: 1031: 100.00		DNJB1_HUMAN (106-371): 9.68e-44: 156: 24.55
+	Hs
		528577 CFTR_HUMAN (1-1480): 0: 1031: 100.00		DNJB2_HUMAN (108-247): 1.07e-42: 153: 32.88
+	Hs
		529482 CFTR_HUMAN (1-1480): 0: 1031: 100.00		DNJB3_HUMAN (108-215): 5.22e-44: 151: 40.54
+	Hs
		528635 CFTR_HUMAN (1-1480): 0: 1031: 100.00		DNJA1_HUMAN (105-209): 7.48e-17: 83.2: 48.57
+	Hs
		529849 CFTR_HUMAN (1-1480): 0: 1031: 100.00		DJB11_HUMAN (107-183): 9.32e-16: 79.7: 50.00