HitPredict

Interactor 1: CFTR (P13569)
Cystic fibrosis transmembrane conductance regulator (CFTR) (ATP-binding cassette sub-family C member 7) (Channel conductance-controlling ATPase) (EC 5.6.1.6) (cAMP-dependent chloride channel)
Gene: CFTR

Interactor 2: PDLI5 (Q96HC4)
PDZ and LIM domain protein 5 (Enigma homolog) (Enigma-like PDZ and LIM domains protein)
Gene: PDLIM5

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.54	0.60	0.571

Property	Details
Experiments	31324722, 29924966
Identification Methods	affinity chromatography technology, pull down
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0016020 - membrane
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 1480 Hs			1 596
+	Hs
		529858 CFTR_HUMAN (1-1480): 0: 1031: 100.00		TES_HUMAN (278-593): 3.29e-62: 213: 18.29
+	Hs
		528764 CFTR_HUMAN (1-1480): 0: 1031: 100.00		PAXI_HUMAN (98-534): 3.23e-32: 133: 13.50
+	Hs
		529770 CFTR_HUMAN (1-1480): 0: 1031: 100.00		PDLI7_HUMAN (475-594): 1.12e-28: 121: 28.33
+	Hs
		117248 CFTR_HUMAN (1-1480): 0: 1031: 100.00		PDLI1_HUMAN (1-172): 4.24e-24: 105: 37.17
+	Hs
		529169 CFTR_HUMAN (1-1480): 0: 1031: 100.00		TRIP6_HUMAN (99-542): 4.54e-22: 101: 14.71