HitPredict

Interactor 1: CFTR (P13569)
Cystic fibrosis transmembrane conductance regulator (CFTR) (ATP-binding cassette sub-family C member 7) (Channel conductance-controlling ATPase) (EC 5.6.1.6) (cAMP-dependent chloride channel)
Gene: CFTR

Interactor 2: COR1C (Q9ULV4)
Coronin-1C (Coronin-3) (hCRNN4)
Gene: CORO1C

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.60	0.60	0.601

Property	Details
Experiments	31324722, 29924966
Identification Methods	affinity chromatography technology, pull down, cross-linking study
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0010008 - endosome membrane
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 1480 Hs			1 474
+	Hs
		529641 CFTR_HUMAN (1-1480): 0: 1031: 100.00		COR1B_HUMAN (2-472): 1.75e-120: 362: 72.14
+	Hs
		529036 CFTR_HUMAN (1-1480): 0: 1031: 100.00		RBBP4_HUMAN (129-345): 4.31e-24: 106: 15.39
+	Hs
		529981 CFTR_HUMAN (1-1480): 0: 1031: 100.00		WSB1_HUMAN (145-313): 6.42e-16: 81.6: 22.09
+	Hs
		529361 CFTR_HUMAN (1-1480): 0: 1031: 100.00		WDR5B_HUMAN (250-381): 2.07e-14: 76.1: 9.70
+	Hs
		706697 MRP1_HUMAN (810-1471): 5.31e-60: 229: 15.70		WDR5_HUMAN (257-397): 3.67e-15: 78.4: 8.39