Interactor 1: ITA4 (P13612)
Integrin alpha-4 (CD49 antigen-like family member D) (Integrin alpha-IV) (VLA-4 subunit alpha) (CD antigen CD49d)
Gene: ITGA4

Interactor 2: FAK1 (Q05397)
Focal adhesion kinase 1 (FADK 1) (EC 2.7.10.2) (Focal adhesion kinase-related nonkinase) (FRNK) (Protein phosphatase 1 regulatory subunit 71) (PPP1R71) (Protein-tyrosine kinase 2) (p125FAK) (pp125FAK)
Gene: PTK2

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.38 0.60 0.479

The method score is based on:

Property Details
Experiments 11919182
Identification Methods affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005178 - integrin binding
GO:0005886 - plasma membrane
GO:0005925 - focal adhesion
GO:0007229 - integrin-mediated signaling pathway
Homologous interactions 7

Homologous interactions

Color coding for hit scores

1 1032
Hs

1 1052
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Mm

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Last updated: 15 Jul 2024