HitPredict

Interactor 1: EF2 (P13639)
Elongation factor 2 (EF-2) (EC 3.6.5.-)
Gene: EEF2

Interactor 2: CUL3 (Q13618)
Cullin-3 (CUL-3)
Gene: CUL3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	35563538, 21145461
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0016020 - membrane and 1 others more... GO:0070062 - extracellular exosome
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 858 Hs			1 768
+	Mm
		885418 EF2_MOUSE (1-858): 0: 1015: 99.07		CUL3_MOUSE (1-768): 0: 949: 99.48
+	Hs
		531145 EF2_HUMAN (1-858): 0: 1013: 100.00		CUL4B_HUMAN (5-768): 0: 779: 36.77
+	Hs
		1041602 U5S1_HUMAN (4-856): 0: 815: 38.37		CUL3_HUMAN (1-768): 0: 951: 100.00
+	Hs
		531143 EF2_HUMAN (1-858): 0: 1013: 100.00		CUL1_HUMAN (18-768): 0: 707: 30.57
+	Hs
		531233 EF2_HUMAN (1-858): 0: 1013: 100.00		CUL5_HUMAN (25-768): 0: 597: 23.77
+	Hs
		1042994 U5S1_HUMAN (4-856): 0: 815: 38.37		CUL4A_HUMAN (10-768): 0: 791: 38.32
+	Sc
		687505 EF2_YEAST (1-858): 0: 943: 65.97		CDC53_YEAST (30-768): 0: 573: 22.08
+	Hs
		1064565 U5S1_HUMAN (4-856): 0: 815: 38.37		CUL5_HUMAN (25-768): 0: 597: 23.77