HitPredict

Interactor 1: K2C5 (P13647)
Keratin, type II cytoskeletal 5 (58 kDa cytokeratin) (Cytokeratin-5) (CK-5) (Keratin-5) (K5) (Type-II keratin Kb5)
Gene: KRT5

Interactor 2: KT33B (Q14525)
Keratin, type I cuticular Ha3-II (Hair keratin, type I Ha3-II) (Keratin-33B) (K33B)
Gene: KRT33B

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.621

Property	Details
Experiments	36949045
Identification Methods	two hybrid
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	Filament~Filament
Common GO terms	GO:0005829 - cytosol GO:0005882 - intermediate filament GO:0045109 - intermediate filament organization GO:0070062 - extracellular exosome
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 590 Hs			1 404
+	Hs
		280847 K2C3_HUMAN (140-484): 3.95e-178: 519: 78.10		KRT37_HUMAN (17-398): 9.79e-151: 435: 61.10
+	Hs
		517761 K2C3_HUMAN (140-484): 3.95e-178: 519: 78.10		K1C40_HUMAN (6-402): 5.14e-145: 420: 59.65
+	Hs
		359297 K2C3_HUMAN (140-484): 3.95e-178: 519: 78.10		K1C14_HUMAN (54-367): 2.81e-143: 417: 60.51
+	Hs
		444302 K2C3_HUMAN (140-484): 3.95e-178: 519: 78.10		K1C19_HUMAN (49-366): 1.39e-142: 413: 55.98
+	Hs
		517762 K2C3_HUMAN (140-484): 3.95e-178: 519: 78.10		K1C39_HUMAN (40-399): 1.66e-128: 380: 61.56
+	Hs
		444997 K2C3_HUMAN (140-484): 3.95e-178: 519: 78.10		K1C16_HUMAN (54-369): 2.62e-110: 333: 59.81
+	Hs
		517737 K2C3_HUMAN (140-484): 3.95e-178: 519: 78.10		K1C15_HUMAN (55-367): 8.45e-107: 323: 57.33
+	Hs
		517735 K2C3_HUMAN (140-484): 3.95e-178: 519: 78.10		K1C13_HUMAN (50-373): 3.03e-104: 317: 55.08
+	Hs
		49556 K22E_HUMAN (140-484): 3.01e-174: 509: 71.88		A1A4E9_HUMAN (50-373): 2.08e-103: 315: 54.46
+	Hs
		280946 K2C3_HUMAN (140-484): 3.95e-178: 519: 78.10		KRT38_HUMAN (9-403): 3.34e-92: 286: 62.12
+	Hs
		280517 K2C3_HUMAN (140-484): 3.95e-178: 519: 78.10		KRT34_HUMAN (1-388): 2.98e-92: 284: 89.95
+	Hs
		318771 K2C3_HUMAN (140-484): 3.95e-178: 519: 78.10		K2C75_HUMAN (21-381): 6.17e-90: 283: 25.34
+	Hs
		517740 K2C3_HUMAN (140-484): 3.95e-178: 519: 78.10		K1C20_HUMAN (52-366): 1.09e-90: 281: 49.84
+	Hs
		280536 K22E_HUMAN (140-484): 3.01e-174: 509: 71.88		KRT34_HUMAN (1-388): 2.98e-92: 284: 89.95
+	Hs
		517752 K2C3_HUMAN (140-484): 3.95e-178: 519: 78.10		K1H2_HUMAN (5-402): 4.61e-84: 265: 66.67
+	Hs
		517773 K2C3_HUMAN (140-484): 3.95e-178: 519: 78.10		KRT35_HUMAN (2-402): 3.37e-80: 255: 67.41
+	Hs
		517751 K2C3_HUMAN (140-484): 3.95e-178: 519: 78.10		KT33B_HUMAN (1-404): 4.27e-80: 253: 100.00
+	Hs
		517754 K2C3_HUMAN (140-484): 3.95e-178: 519: 78.10		K1H1_HUMAN (1-392): 8.95e-80: 253: 94.64
+	Hs
		280772 K2C3_HUMAN (140-484): 3.95e-178: 519: 78.10		KRT36_HUMAN (4-403): 3.13e-78: 250: 68.75
+	Hs
		280777 K22E_HUMAN (140-484): 3.01e-174: 509: 71.88		KRT36_HUMAN (4-403): 3.13e-78: 250: 68.75