HitPredict

Interactor 1: PDIA4 (P13667)
Protein disulfide-isomerase A4 (EC 5.3.4.1) (Endoplasmic reticulum resident protein 70) (ER protein 70) (ERp70) (Endoplasmic reticulum resident protein 72) (ER protein 72) (ERp-72) (ERp72)
Gene: PDIA4

Interactor 2: RON (Q04912)
Macrophage-stimulating protein receptor (MSP receptor) (EC 2.7.10.1) (CDw136) (Protein-tyrosine kinase 8) (p185-Ron) (CD antigen CD136) [Cleaved into: Macrophage-stimulating protein receptor alpha chain; Macrophage-stimulating protein receptor beta chain]
Gene: MST1R

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	35384245
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0009986 - cell surface
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 645 Hs			1 1400
+	Hs
		441417 PDIA4_HUMAN (1-645): 0: 571: 100.00		MET_HUMAN (1-1391): 0: 1065: 32.44
+	Hs
		423211 PDIA1_HUMAN (4-165): 4.25e-32: 132: 27.11		RON_HUMAN (19-1400): 0: 1277: 100.00
+	Mm
		101601 TXND5_MOUSE (285-645): 3.7e-41: 156: 18.73		F8VQL0_MOUSE (1-1362): 0: 1072: 33.64
+	Hs
		531732 PDIA4_HUMAN (1-645): 0: 571: 100.00		EPHB2_HUMAN (557-1369): 6.07e-165: 525: 17.12
+	Hs
		531731 PDIA4_HUMAN (1-645): 0: 571: 100.00		EPHA8_HUMAN (568-1368): 1.37e-159: 509: 17.12
+	Hs
		507820 PDIA4_HUMAN (1-645): 0: 571: 100.00		FGFR1_HUMAN (767-1397): 8.56e-114: 379: 22.74
+	Hs
		531813 PDIA4_HUMAN (1-645): 0: 571: 100.00		MERTK_HUMAN (1037-1348): 1.21e-59: 225: 37.65
+	Hs
		531806 PDIA4_HUMAN (1-645): 0: 571: 100.00		TYRO3_HUMAN (1062-1348): 1.01e-59: 224: 41.95
+	Hs
		531743 PDIA4_HUMAN (1-645): 0: 571: 100.00		RYK_HUMAN (1050-1348): 3.57e-61: 223: 39.42
+	Hs
		531740 PDIA4_HUMAN (1-645): 0: 571: 100.00		UFO_HUMAN (1062-1348): 3.97e-56: 213: 40.47
+	Hs
		435520 PDIA4_HUMAN (1-645): 0: 571: 100.00		IGF1R_HUMAN (1072-1343): 3.56e-52: 204: 37.93
+	Hs
		411285 PDIA4_HUMAN (1-645): 0: 571: 100.00		INSR_HUMAN (1073-1338): 8.47e-51: 199: 38.73
+	Hs
		423118 PDIA1_HUMAN (4-165): 4.25e-32: 132: 27.11		FGFR1_HUMAN (767-1397): 8.56e-114: 379: 22.74
+	Hs
		674477 DJC10_HUMAN (41-295): 2.22e-45: 174: 22.47		UFO_HUMAN (1062-1348): 3.97e-56: 213: 40.47
+	Hs
		435692 DJC10_HUMAN (41-295): 2.22e-45: 174: 22.47		IGF1R_HUMAN (1072-1343): 3.56e-52: 204: 37.93
+	Hs
		411430 DJC10_HUMAN (41-295): 2.22e-45: 174: 22.47		INSR_HUMAN (1073-1338): 8.47e-51: 199: 38.73
+	Hs
		423154 PDIA1_HUMAN (4-165): 4.25e-32: 132: 27.11		UFO_HUMAN (1062-1348): 3.97e-56: 213: 40.47
+	Hs
		423108 PDIA1_HUMAN (4-165): 4.25e-32: 132: 27.11		IGF1R_HUMAN (1072-1343): 3.56e-52: 204: 37.93
+	Hs
		411271 PDIA1_HUMAN (4-165): 4.25e-32: 132: 27.11		INSR_HUMAN (1073-1338): 8.47e-51: 199: 38.73
+	Hs
		411391 PDIA6_HUMAN (57-283): 2.92e-31: 128: 28.51		INSR_HUMAN (1073-1338): 8.47e-51: 199: 38.73