HitPredict

Interactor 1: PDIA4 (P13667)
Protein disulfide-isomerase A4 (EC 5.3.4.1) (Endoplasmic reticulum resident protein 70) (ER protein 70) (ERp70) (Endoplasmic reticulum resident protein 72) (ER protein 72) (ERp-72) (ERp72)
Gene: PDIA4

Interactor 2: EDEM3 (Q9BZQ6)
ER degradation-enhancing alpha-mannosidase-like protein 3 (EC 3.2.1.113) (Alpha-1,2-mannosidase EDEM3)
Gene: EDEM3

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	28366632
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005783 - endoplasmic reticulum GO:0005788 - endoplasmic reticulum lumen
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 645 Hs			1 932
+	Hs
		1220461 DJC10_HUMAN (41-295): 2.22e-45: 174: 22.47		EDEM3_HUMAN (1-932): 0: 1458: 100.00
+	Hs
		423351 PDIA1_HUMAN (4-165): 4.25e-32: 132: 27.11		EDEM3_HUMAN (1-932): 0: 1458: 100.00
+	Hs
		671915 PDIA3_HUMAN (7-188): 4.76e-28: 120: 28.35		EDEM3_HUMAN (1-932): 0: 1458: 100.00
+	Hs
		1240419 TXND5_HUMAN (547-631): 1.03e-21: 100: 34.48		EDEM3_HUMAN (1-932): 0: 1458: 100.00
+	Hs
		531924 PDIA4_HUMAN (1-645): 0: 571: 100.00		EDEM1_HUMAN (43-514): 0: 605: 42.42
+	Hs
		1220441 DJC10_HUMAN (41-295): 2.22e-45: 174: 22.47		EDEM1_HUMAN (43-514): 0: 605: 42.42
+	Hs
		423344 PDIA1_HUMAN (4-165): 4.25e-32: 132: 27.11		EDEM2_HUMAN (19-535): 0: 618: 37.62
+	Hs
		423311 PDIA1_HUMAN (4-165): 4.25e-32: 132: 27.11		EDEM1_HUMAN (43-514): 0: 605: 42.42
+	Sc
		572779 PDI_YEAST (523-645): 2.02e-24: 109: 24.39		MNL1_YEAST (41-513): 0: 549: 35.28
+	Sc
		690739 EUG1_YEAST (51-170): 7.15e-15: 79.8: 27.56		MNL1_YEAST (41-513): 0: 549: 35.28