Interactor 1: CH60 (P10809)
60 kDa heat shock protein, mitochondrial (EC 5.6.1.7) (60 kDa chaperonin) (Chaperonin 60) (CPN60) (Heat shock protein 60) (HSP-60) (Hsp60) (Heat shock protein family D member 1) (HuCHA60) (Mitochondrial matrix protein P1) (P60 lymphocyte protein)
Gene: HSPD1

Interactor 2: CH60 (P10809)
60 kDa heat shock protein, mitochondrial (EC 5.6.1.7) (60 kDa chaperonin) (Chaperonin 60) (CPN60) (Heat shock protein 60) (HSP-60) (Hsp60) (Heat shock protein family D member 1) (HuCHA60) (Mitochondrial matrix protein P1) (P60 lymphocyte protein)
Gene: HSPD1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.86 1.00 0.931

The method score is based on:

Property Details
Experiments 29568061, 37071682, 25253489, 39358380, 31839598, 39349928
Identification Methods proximity labelling technology, cross-linking study
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Cpn60_TCP1~Cpn60_TCP1
Common GO terms GO:0001530 - lipopolysaccharide binding
GO:0002039 - p53 binding
GO:0002755 - MyD88-dependent toll-like receptor signaling pathway
GO:0002842 - positive regulation of T cell mediated immune response to tumor cell
GO:0003688 - DNA replication origin binding
and 61 others

more...

Homologous interactions 8

Homologous interactions

Color coding for hit scores

1 573
Hs

1 573
+ Mm
+ Dm
+ Mm
+ At
+ Sc
+ Ec
+ Hs
+ Zm

Service provided by Combinatics, Japan

Last updated: 11Aug2025