Protein: CH60
60 kDa heat shock protein, mitochondrial (EC 5.6.1.7) (60 kDa chaperonin) (Chaperonin 60) (CPN60) (HSP-65) (Heat shock protein 60) (HSP-60) (Hsp60) (Mitochondrial matrix protein P1)

Gene: CH60, Hspd1
Organism: Mus musculus
Interactions: 51
UniProt ID: P63038

Gene Ontology (top 5):
GO:0001530 - lipopolysaccharide binding
GO:0002039 - p53 binding
GO:0002755 - MyD88-dependent toll-like receptor signaling pathway
GO:0002842 - positive regulation of T cell mediated immune response to tumor cell
GO:0003725 - double-stranded RNA binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

989436

CH60
60 kDa heat shock protein, mitochondrial

3

12

High-throughput

0.827

High

989448

CH10
10 kDa heat shock protein, mitochondrial

1

7

High-throughput

0.618

High

989457

A16L1
Autophagy-related protein 16-1

1

20

High-throughput

0.618

High

989460

EED
Polycomb protein EED

1

20

High-throughput

0.618

High

62343

A4FUW1
Regulatory-associated protein of mTOR

1

20

Small-scale

0.553

High

868834

CRKL
Crk-like protein

1

6

High-throughput

0.536

High

989440

KCMA1
Calcium-activated potassium channel subunit alpha-1

1

7

High-throughput

0.536

High

989467

NPHP1
Nephrocystin-1

1

1

High-throughput

0.536

High

989466

ITA2B
Integrin alpha-IIb

1

7

High-throughput

0.501

High

989464

SPAG6
Sperm-associated antigen 6

1

1

High-throughput

0.481

High

989468

ECSIT
Evolutionarily conserved signaling intermediate in Toll pathway, mitochondrial

1

0

Small-scale

0.479

High

108601

G3X9H5
Huntingtin

1

4

High-throughput

0.479

High

469593

MDHM
Malate dehydrogenase, mitochondrial

1

4

High-throughput

0.479

High

530771

TAU
Microtubule-associated protein tau

1

7

High-throughput

0.479

High

629221

PO5F1
POU domain, class 5, transcription factor 1

1

3

High-throughput

0.479

High

944131

UBP25
Ubiquitin carboxyl-terminal hydrolase 25

1

8

Small-scale

0.479

High

965978

HNRPK
Heterogeneous nuclear ribonucleoprotein K

1

5

High-throughput

0.479

High

989439

ATPA
ATP synthase F(1) complex subunit alpha, mitochondrial

1

8

High-throughput

0.479

High

989441

STING
Stimulator of interferon genes protein

1

2

High-throughput

0.479

High

989442

UBP48
Ubiquitin carboxyl-terminal hydrolase 48

1

5

High-throughput

0.479

High

989445

RASH
GTPase HRas

1

6

Small-scale

0.479

High

989447

TFE3
Transcription factor E3

1

4

High-throughput

0.479

High

989452

NEB2
Neurabin-2

1

7

High-throughput

0.479

High

989453

FACD2
Fanconi anemia group D2 protein homolog

1

4

High-throughput

0.479

High

989454

Q80X68
Citrate synthase

1

3

High-throughput

0.479

High

989461

FBX32
F-box only protein 32

1

3

High-throughput

0.479

High

989463

ETFB
Electron transfer flavoprotein subunit beta

1

2

High-throughput

0.479

High

989465

TLR4
Toll-like receptor 4

1

6

Small-scale

0.479

High

947656

NPHP4
Nephrocystin-4

1

0

High-throughput

0.458

High

989438

PRDX5
Peroxiredoxin-5, mitochondrial

1

0

High-throughput

0.458

High

989444

CLU
Clustered mitochondria protein homolog

1

0

High-throughput

0.458

High

989450

TEDC2
Tubulin epsilon and delta complex protein 2

1

0

High-throughput

0.458

High

989451

Q6GTZ3
Idb1 protein

1

0

Small-scale

0.458

High

989462

GAL3A
Glutamine amidotransferase-like class 1 domain-containing protein 3, mitochondrial

1

0

High-throughput

0.458

High

236655

IKBE
NF-kappa-B inhibitor epsilon

1

9

High-throughput

0.445

High

237360

ILK
Scaffold protein ILK

1

6

Small-scale

0.445

High

569616

AT1B1
Sodium/potassium-transporting ATPase subunit beta-1

1

1

High-throughput

0.445

High

591032

KPCE
Protein kinase C epsilon type

1

2

Small-scale

0.445

High

651505

CBL
E3 ubiquitin-protein ligase CBL

1

7

High-throughput

0.445

High

989437

THIOM
Thioredoxin, mitochondrial

1

4

High-throughput

0.445

High

989443

SHAN3
SH3 and multiple ankyrin repeat domains protein 3

1

2

High-throughput

0.445

High

989446

DLG4
Disks large homolog 4

1

3

High-throughput

0.445

High

398291

CFAD
Complement factor D

1

1

High-throughput

0.437

High

989456

BACD1
BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 1

1

2

High-throughput

0.437

High

989458

MT21E
Protein-lysine methyltransferase METTL21E

1

20

High-throughput

0.437

High

989459

FNDC5
Fibronectin type III domain-containing protein 5

1

1

High-throughput

0.437

High

905808

CAV3
Caveolin-3

1

0

High-throughput

0.426

High

59723

A2APS1
Nephrocystin-1

1

1

High-throughput

0.407

High

989449

Q6AXH7
Histone-lysine N-methyltransferase EZH2

1

15

High-throughput

0.407

High

989455

NANOG
Homeobox protein NANOG

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025