HitPredict

Interactor 1: PRG2 (P13727)
Bone marrow proteoglycan (BMPG) (Proteoglycan 2) [Cleaved into: Eosinophil granule major basic protein (EMBP) (MBP) (Pregnancy-associated major basic protein)]
Gene: PRG2

Interactor 2: EGFL7 (Q9UHF1)
Epidermal growth factor-like protein 7 (EGF-like protein 7) (Multiple epidermal growth factor-like domains protein 7) (Multiple EGF-like domains protein 7) (NOTCH4-like protein) (Vascular endothelial statin) (VE-statin) (Zneu1)
Gene: EGFL7

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005576 - extracellular region GO:0062023 - collagen-containing extracellular matrix
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 222 Hs			1 273
+	Hs
		426883 ASGR2_HUMAN (5-221): 6.71e-41: 143: 16.30		EGFL7_HUMAN (1-273): 1.56e-39: 140: 100.00
+	Hs
		532955 PRG2_HUMAN (1-222): 3.43e-57: 182: 100.00		GAS6_HUMAN (54-186): 3.87e-20: 91.8: 25.18
+	Hs
		423069 PRG2_HUMAN (1-222): 3.43e-57: 182: 100.00		PROS_HUMAN (43-186): 1.23e-19: 90.2: 22.50
+	Hs
		149947 NCAN_HUMAN (16-221): 1.24e-45: 163: 16.80		TENA_HUMAN (2-259): 1.79e-25: 107: 15.97
+	Rn
		70327 G3V8R2_RAT (3-221): 2.12e-51: 180: 18.29		B2LYI9_RAT (54-272): 7.18e-19: 88.4: 15.23
+	Hs
		296680 PRG3_HUMAN (12-222): 3.37e-54: 174: 49.30		SLIT2_HUMAN (3-138): 1.42e-12: 69.5: 11.77
+	Hs
		532909 PRG2_HUMAN (1-222): 3.43e-57: 182: 100.00		NOTC1_HUMAN (80-168): 1.88e-09: 60.1: 21.81
+	Hs
		533087 PRG2_HUMAN (1-222): 3.43e-57: 182: 100.00		CELR1_HUMAN (28-152): 9.41e-09: 58.3: 18.35