HitPredict

Interactor 1: PRG2 (P13727)
Bone marrow proteoglycan (BMPG) (Proteoglycan 2) [Cleaved into: Eosinophil granule major basic protein (EMBP) (MBP) (Pregnancy-associated major basic protein)]
Gene: PRG2

Interactor 2: ADA21 (Q9UKJ8)
Disintegrin and metalloproteinase domain-containing protein 21 (ADAM 21) (EC 3.4.24.-)
Gene: ADAM21

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.80	0.618

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	ADAM_CR~Lectin_C
Common GO terms	-
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 222 Hs			1 722
+	Hs
		532946 PRG2_HUMAN (1-222): 3.43e-57: 182: 100.00		ADAM9_HUMAN (26-722): 0: 570: 35.25
+	Hs
		532947 PRG2_HUMAN (1-222): 3.43e-57: 182: 100.00		ADA15_HUMAN (58-665): 1.72e-130: 409: 29.46
+	Hs
		426866 ASGR2_HUMAN (5-221): 6.71e-41: 143: 16.30		ADA33_HUMAN (78-683): 1.48e-125: 394: 30.02
+	Hs
		1292817 PGCB_HUMAN (10-221): 9.83e-54: 186: 17.20		ATS7_HUMAN (21-656): 6.21e-101: 342: 18.93
+	Hs
		533102 PRG2_HUMAN (1-222): 3.43e-57: 182: 100.00		ATS7_HUMAN (21-656): 6.21e-101: 342: 18.93
+	Hs
		1356546 PRG3_HUMAN (12-222): 3.37e-54: 174: 49.30		ATS7_HUMAN (21-656): 6.21e-101: 342: 18.93
+	Hs
		533096 PRG2_HUMAN (1-222): 3.43e-57: 182: 100.00		ATS1_HUMAN (35-654): 1.07e-98: 327: 15.70
+	Hs
		314538 PRG2_HUMAN (1-222): 3.43e-57: 182: 100.00		ATS2_HUMAN (44-654): 8.34e-96: 324: 17.06
+	Hs
		426828 ASGR2_HUMAN (5-221): 6.71e-41: 143: 16.30		Q08AM2_HUMAN (78-268): 1.11e-30: 130: 20.79
+	Mm
		192925 NCAN_MOUSE (3-221): 2.96e-52: 182: 18.29		ADA10_MOUSE (338-514): 2.03e-11: 69.3: 29.80
+	Hs
		152243 PRG2_HUMAN (1-222): 3.43e-57: 182: 100.00		ADA10_HUMAN (338-514): 6.58e-11: 67.8: 29.65