HitPredict

Interactor 1: PLSL (P13796)
Plastin-2 (L-plastin) (LC64P) (Lymphocyte cytosolic protein 1) (LCP-1)
Gene: LCP1

Interactor 2: PPARG (P37231)
Peroxisome proliferator-activated receptor gamma (PPAR-gamma) (Nuclear receptor subfamily 1 group C member 3)
Gene: PPARG

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	30699358
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 627 Hs			1 505
+	Hs
		368908 PLST_HUMAN (1-627): 0: 646: 79.90		ESR1_HUMAN (1-501): 9.09e-112: 345: 19.28
+	Hs
		1056383 PLSI_HUMAN (2-627): 0: 617: 73.48		ESR2_HUMAN (23-502): 1.79e-98: 308: 18.70
+	Hs
		369446 DYST_HUMAN (105-626): 1.94e-122: 402: 17.94		ESR1_HUMAN (1-501): 9.09e-112: 345: 19.28
+	Hs
		974119 DYST_HUMAN (105-626): 1.94e-122: 402: 17.94		ESR2_HUMAN (23-502): 1.79e-98: 308: 18.70
+	Hs
		211518 ACTN4_HUMAN (378-625): 1.11e-56: 208: 20.23		PPARG_HUMAN (1-505): 2.47e-165: 479: 100.00
+	Hs
		369641 PLEC_HUMAN (382-627): 4.56e-60: 219: 20.78		ESR1_HUMAN (1-501): 9.09e-112: 345: 19.28
+	Hs
		370715 MACF1_HUMAN (379-627): 4.13e-59: 217: 20.62		ESR1_HUMAN (1-501): 9.09e-112: 345: 19.28
+	Hs
		211456 ACTN4_HUMAN (378-625): 1.11e-56: 208: 20.23		ESR1_HUMAN (1-501): 9.09e-112: 345: 19.28
+	Hs
		368893 ACTN1_HUMAN (392-625): 4.81e-57: 208: 21.81		ESR1_HUMAN (1-501): 9.09e-112: 345: 19.28
+	Hs
		320227 SPTN4_HUMAN (390-627): 6.98e-61: 222: 21.60		ERR2_HUMAN (25-502): 1.06e-104: 321: 19.14
+	Hs
		211477 ACTN4_HUMAN (378-625): 1.11e-56: 208: 20.23		VDR_HUMAN (139-503): 4.55e-108: 330: 26.68
+	Hs
		521532 ACTN1_HUMAN (392-625): 4.81e-57: 208: 21.81		NR1H3_HUMAN (52-501): 2.02e-104: 321: 24.78
+	Hs
		1068618 PLEC_HUMAN (382-627): 4.56e-60: 219: 20.78		ESR2_HUMAN (23-502): 1.79e-98: 308: 18.70
+	Hs
		1269937 MACF1_HUMAN (379-627): 4.13e-59: 217: 20.62		ESR2_HUMAN (23-502): 1.79e-98: 308: 18.70
+	Hs
		211472 ACTN4_HUMAN (378-625): 1.11e-56: 208: 20.23		RARA_HUMAN (45-503): 3.89e-102: 316: 25.22
+	Mm
		740808 PLEC_MOUSE (376-627): 2.5e-59: 218: 19.55		THB_MOUSE (85-503): 2.56e-97: 303: 24.36
+	Hs
		993279 ACTN3_HUMAN (392-625): 2.08e-58: 213: 22.13		ESR2_HUMAN (23-502): 1.79e-98: 308: 18.70
+	Hs
		164649 SPTN2_HUMAN (381-625): 7.03e-57: 210: 24.61		ESR2_HUMAN (23-502): 1.79e-98: 308: 18.70
+	Hs
		211633 ACTN4_HUMAN (378-625): 1.11e-56: 208: 20.23		ESR2_HUMAN (23-502): 1.79e-98: 308: 18.70
+	Hs
		521591 ACTN1_HUMAN (392-625): 4.81e-57: 208: 21.81		ESR2_HUMAN (23-502): 1.79e-98: 308: 18.70