Protein: GPA2
Guanine nucleotide-binding protein alpha-2 subunit (GP2-alpha)

Gene: GPA2
Organism: Saccharomyces cerevisiae S288C
Interactions: 64
UniProt ID: P10823

Gene Ontology (top 5):
GO:0001403 - invasive growth in response to glucose limitation
GO:0001664 - G protein-coupled receptor binding
GO:0003924 - GTPase activity
GO:0005525 - GTP binding
GO:0005737 - cytoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

470729

GPA1
Guanine nucleotide-binding protein alpha-1 subunit

2

13

Small-scale

0.799

High

533172

GPB2
Guanine nucleotide-binding protein subunit beta 2

4

1

Small-scale

0.695

High

475100

CYAA
Adenylate cyclase

1

1

Small-scale

0.692

High

533205

GPR1
G protein-coupled receptor GPR1

4

1

Small-scale

0.691

High

533164

IME2
Meiosis induction protein kinase IME2/SME1

2

2

Small-scale

0.633

High

533169

GBLP
Small ribosomal subunit protein RACK1

1

20

Small-scale

0.618

High

533207

RGS2
Regulator of G-protein signaling 2

1

0

Small-scale

0.614

High

533186

MEP3
Ammonium transporter MEP3

2

1

High-throughput

0.613

High

533158

MCK1
Protein kinase MCK1

1

1

Small-scale

0.561

High

533150

SSB1
Ribosome-associated molecular chaperone SSB1

2

6

High-throughput

0.552

High

533160

SYP1
Suppressor of yeast profilin deletion

1

4

High-throughput

0.541

High

533170

RFS1
Protein RFS1

1

1

High-throughput

0.541

High

533171

OSH7
Oxysterol-binding protein homolog 7

1

2

High-throughput

0.541

High

533173

FLC2
Flavin carrier protein 2

1

1

High-throughput

0.541

High

533175

MEP1
Ammonium transporter MEP1

1

1

High-throughput

0.541

High

533180

MUP1
High-affinity methionine permease

1

3

High-throughput

0.541

High

533184

YG3A
Uncharacterized protein YGR130C

1

6

High-throughput

0.541

High

533185

TPO2
Polyamine transporter 2

1

2

High-throughput

0.541

High

533187

WSC2
Cell wall integrity and stress response component 2

1

1

High-throughput

0.541

High

533188

OSH6
Oxysterol-binding protein homolog 6

1

2

High-throughput

0.541

High

533193

TPO3
Polyamine transporter 3

1

2

High-throughput

0.541

High

533201

WSC3
Cell wall integrity and stress response component 3

1

1

High-throughput

0.541

High

533203

TPO4
Polyamine transporter 4

1

2

High-throughput

0.541

High

533204

PST2
Protoplast secreted protein 2

1

1

High-throughput

0.541

High

533156

PMA2
Plasma membrane ATPase 2

1

3

High-throughput

0.536

High

533157

HNM1
Choline transporter

1

0

High-throughput

0.518

High

533159

HSP30
30 kDa heat shock protein

1

0

High-throughput

0.518

High

533163

RIM1
Single-stranded DNA-binding protein RIM1, mitochondrial

1

0

High-throughput

0.518

High

533166

DUR3
Urea active transporter

1

0

High-throughput

0.518

High

533167

SFK1
Protein SFK1

1

0

High-throughput

0.518

High

533168

MID2
Cell wall integrity sensor MID2

1

0

High-throughput

0.518

High

533174

FTR1
Plasma membrane iron permease

1

0

High-throughput

0.518

High

533176

SLM1
Phosphatidylinositol 4,5-bisphosphate-binding protein SLM1

1

0

High-throughput

0.518

High

533179

YJB6
Uncharacterized protein YJL016W

1

0

High-throughput

0.518

High

533181

YOR1
Oligomycin resistance ATP-dependent permease YOR1

1

0

High-throughput

0.518

High

533183

YGK8
Uncharacterized protein YGL108C

1

0

High-throughput

0.518

High

533189

PDR12
ATP-dependent permease PDR12

1

0

High-throughput

0.518

High

533195

YL413
Cell membrane protein YLR413W

1

0

High-throughput

0.518

High

533206

YB029
UPF0768 protein YBL029C-A

1

0

High-throughput

0.518

High

533153

HSC82
ATP-dependent molecular chaperone HSC82

1

4

High-throughput

0.515

High

533161

IDH1
Isocitrate dehydrogenase [NAD] subunit 1, mitochondrial

1

0

High-throughput

0.513

High

533178

SYEC
Glutamate--tRNA ligase, cytoplasmic

1

0

High-throughput

0.513

High

533191

FAR8
Factor arrest protein 8

1

0

High-throughput

0.513

High

533151

ODP2
Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial

1

1

High-throughput

0.500

High

533197

THI20
Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase THI20

1

1

High-throughput

0.500

High

533200

THI21
Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase THI21

1

1

High-throughput

0.500

High

533199

FLC1
Flavin carrier protein 1

1

1

High-throughput

0.494

High

533182

GPG1
Heterotrimeric G protein gamma subunit GPG1

1

0

Small-scale

0.486

High

533155

MYO2
Myosin-2

1

3

Small-scale

0.481

High

394151

EF1A
Elongation factor 1-alpha

1

0

High-throughput

0.479

High

416351

HXKA
Hexokinase-1

1

0

High-throughput

0.479

High

533177

MPG1
Mannose-1-phosphate guanyltransferase

1

0

High-throughput

0.479

High

533152

KSS1
Mitogen-activated protein kinase KSS1

1

2

Small-scale

0.479

High

533154

FUS3
Mitogen-activated protein kinase FUS3

1

2

Small-scale

0.479

High

533198

GPB1
Guanine nucleotide-binding protein subunit beta 1

1

1

Small-scale

0.479

High

533202

YGK3
Glycogen synthase kinase-3 homolog YGK3

1

1

Small-scale

0.457

High

522847

HSP71
Heat shock protein SSA1

1

7

High-throughput

0.445

High

525738

HSP72
Heat shock protein SSA2

1

7

High-throughput

0.445

High

533194

SWA2
Auxilin-like clathrin uncoating factor SWA2

1

5

High-throughput

0.445

High

533190

TCB3
Tricalbin-3

1

0

High-throughput

0.438

High

533196

FMP45
SUR7 family protein FMP45

1

0

High-throughput

0.438

High

533162

PLC1
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase 1

1

4

Small-scale

0.437

High

533165

RSSA1
Small ribosomal subunit protein uS2A

1

0

High-throughput

0.426

High

533192

YL326
Uncharacterized membrane protein YLR326W

1

0

High-throughput

0.282

High


Service provided by Combinatics, Japan

Last updated: 11Aug2025