HitPredict

Interactor 1: GYS1 (P13807)
Glycogen [starch] synthase, muscle (EC 2.4.1.11) (Glycogen synthase 1)
Gene: GYS1

Interactor 2: PP1A (P62136)
Serine/threonine-protein phosphatase PP1-alpha catalytic subunit (PP-1A) (EC 3.1.3.16)
Gene: PPP1CA

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.87	0.60	0.723

Property	Details
Experiments	26186194, 28514442, 27173435, 28330616, 33961781
Identification Methods	affinity chromatography technology, proximity labelling technology, tandem affinity purification, pull down, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 737 Hs			1 330
+	Mm
		906390 GYS1_MOUSE (1-737): 0: 1388: 96.61		PP1A_MOUSE (1-330): 0: 614: 99.70
+	Hs
		533651 GYS1_HUMAN (1-737): 0: 1422: 100.00		PP1G_HUMAN (1-330): 0: 579: 90.66
+	Hs
		533662 GYS1_HUMAN (1-737): 0: 1422: 100.00		PP1B_HUMAN (1-330): 0: 568: 87.88
+	Hs
		873220 GYS2_HUMAN (1-658): 0: 1118: 72.53		PP1A_HUMAN (1-330): 0: 614: 100.00
+	Sc
		615352 GYS1_YEAST (23-660): 0: 1066: 54.49		PP12_YEAST (3-307): 0: 551: 84.26
+	Sc
		648302 GYS2_YEAST (23-660): 0: 1061: 53.96		PP12_YEAST (3-307): 0: 551: 84.26