Interactor 1: BIP (P11021)
Endoplasmic reticulum chaperone BiP (EC 3.6.4.10) (78 kDa glucose-regulated protein) (GRP-78) (Binding-immunoglobulin protein) (BiP) (Heat shock protein 70 family protein 5) (HSP70 family protein 5) (Heat shock protein family A member 5) (Immunoglobulin heavy chain-binding protein)
Gene: HSPA5
Interactor 2: CALR3 (Q96L12)
Calreticulin-3 (Calreticulin-2) (Calsperin)
Gene: CALR3
Species: Homo sapiens
Source: biogrid
Category: High-throughput
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.56 | 0.60 | 0.584 |
The method score is based on:
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | - |
| Common GO terms | GO:0005788 - endoplasmic reticulum lumen GO:0005789 - endoplasmic reticulum membrane GO:0036503 - ERAD pathway GO:0044183 - protein folding chaperone GO:0051082 - unfolded protein binding |
| Homologous interactions | 4 |
Homologous interactions
Color coding for hit scores 
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Last updated: 11Aug2025
