HitPredict

Interactor 1: BIP (P11021)
Endoplasmic reticulum chaperone BiP (EC 3.6.4.10) (78 kDa glucose-regulated protein) (GRP-78) (Binding-immunoglobulin protein) (BiP) (Heat shock protein 70 family protein 5) (HSP70 family protein 5) (Heat shock protein family A member 5) (Immunoglobulin heavy chain-binding protein)
Gene: HSPA5

Interactor 2: GNB1L (Q9BYB4)
Guanine nucleotide-binding protein subunit beta-like protein 1 (G protein subunit beta-like protein 1) (DGCRK3) (WD repeat-containing protein 14) (WD40 repeat-containing protein deleted in VCFS) (WDVCF)
Gene: GNB1L

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	33957083
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 654 Hs			1 327
+	Hs
		537845 HSP7C_HUMAN (26-637): 0: 914: 66.02		GNB1L_HUMAN (1-327): 5.23e-100: 299: 100.00
+	Hs
		931096 HSP72_HUMAN (25-636): 0: 903: 64.51		GNB1L_HUMAN (1-327): 5.23e-100: 299: 100.00
+	Hs
		536889 HSP7C_HUMAN (26-637): 0: 914: 66.02		WDR5_HUMAN (1-283): 2.97e-69: 220: 16.32
+	Hs
		534872 BIP_HUMAN (19-654): 0: 913: 100.00		WDR5_HUMAN (1-283): 2.97e-69: 220: 16.32
+	Hs
		537452 HSP7C_HUMAN (26-637): 0: 914: 66.02		WDR5B_HUMAN (5-280): 3.5e-67: 215: 15.30
+	Hs
		536681 HSP7C_HUMAN (26-637): 0: 914: 66.02		LIS1_HUMAN (101-326): 7.12e-57: 191: 15.39
+	Hs
		761452 HS71L_HUMAN (24-647): 0: 919: 63.16		POC1A_HUMAN (165-326): 1.27e-41: 150: 20.86
+	Hs
		537531 HSP7C_HUMAN (26-637): 0: 914: 66.02		POC1A_HUMAN (165-326): 1.27e-41: 150: 20.86
+	Hs
		600864 HSP76_HUMAN (25-635): 0: 913: 62.54		POC1A_HUMAN (165-326): 1.27e-41: 150: 20.86
+	Hs
		537653 HSP7C_HUMAN (26-637): 0: 914: 66.02		FBXW7_HUMAN (1-189): 8.49e-33: 130: 14.29
+	Hs
		536814 HSP7C_HUMAN (26-637): 0: 914: 66.02		COPA_HUMAN (34-323): 7.27e-27: 113: 16.35
+	Hs
		534823 BIP_HUMAN (19-654): 0: 913: 100.00		COPA_HUMAN (34-323): 7.27e-27: 113: 16.35
+	Hs
		536920 HSP7C_HUMAN (26-637): 0: 914: 66.02		GBB2_HUMAN (5-144): 1.57e-19: 89.3: 16.90
+	Hs
		534903 BIP_HUMAN (19-654): 0: 913: 100.00		GBB2_HUMAN (5-144): 1.57e-19: 89.3: 16.90
+	Hs
		600789 HSP76_HUMAN (25-635): 0: 913: 62.54		GBB2_HUMAN (5-144): 1.57e-19: 89.3: 16.90
+	Hs
		516192 HS71B_HUMAN (26-635): 0: 907: 64.11		GBB2_HUMAN (5-144): 1.57e-19: 89.3: 16.90
+	Hs
		930844 HSP72_HUMAN (25-636): 0: 903: 64.51		GBB2_HUMAN (5-144): 1.57e-19: 89.3: 16.90
+	Sc
		597117 BIP_YEAST (22-638): 0: 798: 68.82		GBLP_YEAST (182-323): 1.6e-09: 60.1: 27.52