Interactor 1: EDN3 (P14138)
Endothelin-3 (ET-3) (Preproendothelin-3) (PPET3)
Gene: EDN3

Interactor 2: NOTC1 (P46531)
Neurogenic locus notch homolog protein 1 (Notch 1) (hN1) (Translocation-associated notch protein TAN-1) [Cleaved into: Notch 1 extracellular truncation (NEXT); Notch 1 intracellular domain (NICD)]
Gene: NOTCH1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.47 0.60 0.536

The method score is based on:

Property Details
Experiments 33961781
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005576 - extracellular region
GO:0007411 - axon guidance
GO:0008284 - positive regulation of cell population proliferation
Homologous interactions 2

Homologous interactions

Color coding for hit scores

1 238
Hs

1 2555
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024