HitPredict

Interactor 1: HGF (P14210)
Hepatocyte growth factor (Hepatopoietin-A) (Scatter factor) (SF) [Cleaved into: Hepatocyte growth factor alpha chain; Hepatocyte growth factor beta chain]
Gene: HGF

Interactor 2: FGFR4 (P22455)
Fibroblast growth factor receptor 4 (FGFR-4) (EC 2.7.10.1) (CD antigen CD334)
Gene: FGFR4

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.501

Property	Details
Experiments	28205554
Identification Methods	fluorescent resonance energy transfer
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005576 - extracellular region GO:2000573 - positive regulation of DNA biosynthetic process
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 728 Hs			1 802
+	Hs
		536120 HGF_HUMAN (1-728): 0: 902: 100.00		EPHA2_HUMAN (4-789): 0: 573: 19.58
+	Hs
		428666 TRY1_HUMAN (494-724): 1.88e-94: 295: 32.08		EPHA3_HUMAN (4-778): 0: 595: 18.34
+	Hs
		872605 ST14_HUMAN (247-719): 1.81e-113: 364: 21.70		EPHB4_HUMAN (4-781): 4.88e-171: 521: 17.66
+	Hs
		1072534 TM11B_HUMAN (479-718): 3.92e-93: 297: 24.59		EPHA7_HUMAN (4-781): 0: 584: 19.90
+	Hs
		1072608 TMPS4_HUMAN (454-719): 8.66e-93: 297: 24.82		EPHA7_HUMAN (4-781): 0: 584: 19.90
+	Hs
		872716 TMPS4_HUMAN (454-719): 8.66e-93: 297: 24.82		EPHA4_HUMAN (4-776): 0: 582: 19.47
+	Hs
		872513 TMPS3_HUMAN (470-720): 1.28e-95: 305: 27.63		EPHB4_HUMAN (4-781): 4.88e-171: 521: 17.66
+	Hs
		872570 TMPSD_HUMAN (467-727): 2.13e-92: 301: 27.24		EPHB4_HUMAN (4-781): 4.88e-171: 521: 17.66
+	Hs
		872582 TMPS4_HUMAN (454-719): 8.66e-93: 297: 24.82		EPHB4_HUMAN (4-781): 4.88e-171: 521: 17.66
+	Hs
		409508 HEPS_HUMAN (468-724): 8.02e-92: 294: 27.11		EPHB4_HUMAN (4-781): 4.88e-171: 521: 17.66
+	Hs
		1031147 TM11B_HUMAN (479-718): 3.92e-93: 297: 24.59		PTK7_HUMAN (153-424): 7.29e-20: 97.1: 16.36
+	Hs
		1031173 TMPS4_HUMAN (454-719): 8.66e-93: 297: 24.82		PTK7_HUMAN (153-424): 7.29e-20: 97.1: 16.36